细胞因子在分泌性中耳炎相关免疫机制中的研究进展  

Research Progress of Cytokines in Secretory Otitis Media Related Immune Mechanism

作　　者：刘柯 赵兴泉[2] 钟渠[2] LIU Ke;ZHAO Xing-quan;ZHONG Qu(Department of Otorhinolaryngology,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan,China;Department of Otorhinolaryngology Head and Neck Surgery,the Second Affiliated Hospital of North Sichuan Medical College/Sichuan Mianyang 404 Hospital,Mianyang 621000,Sichuan,China)

机构地区：[1]川北医学院附属医院耳鼻咽喉科,四川南充637000 [2]川北医学院附属第二医院/四川绵阳四〇四医院耳鼻咽喉头颈外科,四川绵阳621000

出　　处：《医学信息》2022年第12期73-76,共4页Journal of Medical Information

基　　金：绵阳市卫计委科研课题立项项目(编号:201744)。

摘　　要：分泌性中耳炎(SOM)是一种耳鼻咽喉科的常见疾病,多以中耳积液及传导性听力下降为主要临床表现,其发病机制尚未完全明确,主要包括咽鼓管功能不良、感染因素以及免疫相关因素等。近年来许多学者针对其免疫相关因素——细胞因子开展了大量的实验研究,初步揭示了细胞因子相关免疫反应和分泌性中耳炎之间有密切的联系。本文将对近年来分泌性中耳炎免疫相关细胞因子的研究进展进行综述,以期为分泌性中耳炎的相关诊治提供参考。Secretory otitis media(SOM) is a common disease in the department of otorhinolaryngology,with effusion in the middle ear and conductive hearing loss as the main clinical manifestations.The pathogenesis of SOM yet been fully clarified,mainly including eustachian tube dysfunction,infection factors and immune-related factors.In recent years,many scholars have carried out a large number of experimental studies on the immunerelated factors-cytokines,which preliminarily revealed the close relationship between cytokine-related immune response and secretory otitis media.This article will review the research progress of immune-related cytokines in secretory otitis media in recent years,in order to provide reference for the diagnosis and treatment of secretory otitis media.

关 键 词：分泌性中耳炎 细胞因子 免疫反应 

分 类 号：R764.21[医药卫生—耳鼻咽喉科]