老年骨质疏松症全髋关节置换后假体无菌性松动的药物防治研究  

Study on Drug Prevention and Treatment of Aseptic Loosening of Prosthesis After Total Hip Arthroplasty in Senile Osteoporosis

作　　者：何浓 张永胜 熊福生 陈泽 HE Nong;ZHANG Yong-sheng;XIONG Fu-sheng;CHEN Ze(Department of Orthopedics,Suining Municipal Hospital of TCM Affiliated to North Sichuan Medical College,Suining 629000,Sichuan,China)

机构地区：[1]川北医学院附属遂宁市中医院骨科,四川遂宁629000

出　　处：《医学信息》2022年第12期77-80,88,共5页Journal of Medical Information

基　　金：白求恩·石药骨质疏松科研基金项目(编号:G-X-2020-1107-6)。

摘　　要：全髋关节置换术是晚期及重度髋关节疾病的有效治疗方法。当前,由于生物材料自身缺陷和人体生物力学等因素影响,并不能保证所有患者术后可以终身正常使用,而髋关节假体无菌性松动则是全髋关节置换术后常见的晚期并发症。老龄化不可避免的会导致骨质疏松,进一步加速假体的松动。本文主要对老年骨质疏松症全髋关节置换后假体无菌性松动的潜在药物防治进展做一综述,以期为后续临床研究提供参考。Total hip arthroplasty is an effective treatment for advanced and severe hip diseases.At present,due to the defects of biological materials and human biomechanics and other factors,it cannot ensure that all patients can be used normally for life after surgery,and aseptic loosening of hip prosthesis is a common late complication after total hip arthroplasty.Aging inevitably leads to osteoporosis and further accelerates prosthesis loosening.This article mainly reviews the potential drug prevention and treatment progress of aseptic loosening of prosthesis after total hip arthroplasty in elderly osteoporosis,in order to provide reference for subsequent clinical research.

关 键 词：老年骨质疏松症 全髋关节置换 假体无菌性松动 

分 类 号：R87.4[医药卫生—运动医学]