产妇产后持续抑郁与婴儿发育行为和社交情绪的相关性  

Relationship between maternal persistent postpartum depression and infant development behavior and social-emotional

作　　者：谢亮亮 严双琴 徐爱枝 姚莉琳 曹慧 翁婷婷 高国朋 蔡智玲 汪素美 陶芳标[2] XIE Liang-Liang;YAN Shuang-Qin;XU Ai-Zhi(Maanshan Maternal and Child Health Hospital,Maanshan,Ma'anshan,Anhui 243000,China)

机构地区：[1]马鞍山市妇幼保健院,安徽马鞍山243000 [2]安徽医科大学,安徽合肥230032

出　　处：《中国妇幼保健》2022年第7期1171-1175,共5页Maternal and Child Health Care of China

基　　金：合生元母婴营养与健康研究项目(2015FYH006,2018FYH009,2019FYH024);安徽省马鞍山市科技计划项目(YL-2015-06)。

摘　　要：目的探讨产妇产后持续抑郁对婴儿发育行为和社交情绪的影响。方法以2015年6月—2016年6月建立的马鞍山市母婴健康队列为基础,随访至婴儿6月龄,获得完整的42 d、3月产后抑郁信息、6月龄“年龄与发育进程问卷第3版”(ASQ-3)及“年龄与发育进程问卷:社交-情绪第3版”(ASQ:SE-3)的资料共1521例。分别在产后42 d和3月龄时,采用“爱丁堡产后抑郁量表(EPDS)”评价产妇产后抑郁程度;在6月龄时,采用“ASQ-3”和“ASQ:SE-3”评价婴儿的发育行为和社交情绪。通过《孕产期母婴健康记录表》和《分娩及新生儿情况记录表》获取社会人口统计学和儿童信息。使用t检验和linear回归模型进行分析。结果产后42 d、3月及产妇产后持续抑郁的检出率分别为303例(19.9%)、175例(11.5%)及87例(5.7%)。调整婴儿性别、分娩方式、孕周、出生体质量、出生时父母年龄、父母文化程度、家庭人均收入及户口等混杂因素后,linear回归分析结果显示,产后42 d产妇抑郁是婴儿精细动作、解决问题及社交-情绪的危险因素(P<0.01),产后3月产妇抑郁是婴儿社交-情绪的危险因素(P<0.001),产妇产后持续抑郁是婴儿精细动作和社交-情感的危险因素(P<0.01)。结论产后42 d抑郁仍处于较高水平,产后持续抑郁也存在一定的比例,且产后抑郁和产后持续抑郁对婴儿精细动作和社交-情感均会产生不良影响,应重视产后产妇的早期筛查和相关干预工作。Objective To explore the effects of maternal persistent postpartum depression on infant development behavior and social-emotional.Methods Based on the birth cohort of Maanshan Maternal and Infant Health from June 2015 to June 2016,the infants were followed up to the age of 6 months.A total of 1521 participants obtained complete 42 day,3-month maternal postpartum depression information and 6-month-old Ages and Stages Questionaire-3(ASQ-3)and Ages and Stages Questionaire-3:Social-emotional-3(ASQ:SE-3).The"Edinburgh Postnatal Depression Scale(EPDS)"was used to evaluate the postpartum depression symptoms of mothers at 42 days and 3 months postnatal age respectively.At the age of 6 months,"ASQ-3"and"ASQ:SE-3"were used to evaluate the infants developmental behaviors and social emotions.Social demography and children’s information were obtained through the maternal and infant health record form and the delivery and newborn situation record form.We used t-test to compare the general characteristics(continuous variables).Linear regression was used.Results The detection rates of maternal postpartum depression in 42 days,3 months and persistent existence were 303(19.9%),175(11.5%)and 87(5.7%)respectively.After adjusting the confounding factors such as infant sex,delivery mode,gestational age,birth weight,age of parents at birth,education level of parents,per capita income of family and household registration,linear regression analysis showed that 42 days postpartum maternal depression was a risk factor of fine movement,problem-solving and social emotion of infants(P<0.01),3 months postpartum maternal depression was a risk factor of infants social emotion(P<0.001),and persistent postpartum depression was a risk factor for fine motor and social emotion(P<0.01).Conclusion Postpartum depression at 42 days after delivery is still at a high level,there is a certain proportion of postpartum persistent depression,and postpartum depression and persistent postpartum depression can have adverse effects on infants fine movement and s

关 键 词：产后抑郁 婴儿 发育 社交情感 

分 类 号：R173[医药卫生—妇幼卫生保健]