糖类抗原19⁃9作为先天性肾积水生化标志物的研究进展  

Research advances of carbohydrate antigen 19⁃9 as a biochemical marker of congenital hydrone⁃phrosis

作　　者：闫动[1] 张蕾[2] 刘超[2] Yan Dong;Zhang Lei;Liu Chao(Department of Anesthesiology,Qilu Hospital,Shandong University,Qingdao 266035,China;Department of Pediatric Surgery,Qilu Hospital,Shandong University,Qingdao 266035,China)

机构地区：[1]山东大学齐鲁医院麻醉科,青岛266035 [2]山东大学齐鲁医院儿外科,青岛266035

出　　处：《中华小儿外科杂志》2022年第5期476-480,共5页Chinese Journal of Pediatric Surgery

基　　金：青岛市医药卫生科研计划项目(2021-WJZD214);山东大学齐鲁医院(青岛)科研启动基金(QDKY2021QN04)。

摘　　要：目前实验室中有多种生化标志物被用于先天性肾积水的病情评估,但一个特定、可靠、操作简便的诊断和预测工具尚未确定。糖类抗原19-9是临床常用的肿瘤生化标志物,它被发现可能与先天性肾积水相关。本研究就糖类抗原19-9在先天性肾积水临床诊治中的研究进展进行综述,以期为先天性肾积水的预测、诊断、治疗和随访等提供参考。Currently a variety of biochemical markers have been employed for assessing the laboratory status of congenital hydronephrosis.However,a specific,reliable and simple diagnostic and predictive tool has not been established.Carbohydrate antigen 19-9 is a commonly used tumor biochemical marker in clinical practice.It may be related to congenital hydronephrosis.This review summarized the research advances of carbohydrate antigen 19-9 in clinical diagnosis and treatment of congenital hydronephrosis.It provided rationales for the prediction,diagnosis,treatment and followups of congenital hydronephrosis.

关 键 词：肾盂积水 糖类抗原19-9 生物标记 

分 类 号：R726.9[医药卫生—儿科]