比较基于舒芬太尼和芬太尼的静脉患者自控镇痛对腹腔镜肾切除术后恶心和呕吐的影响  

Comparison of effects of sufentanil and fentanyl-based intravenous patient-controlled analgesia on nausea and vomiting after laparoscopic nephrectomy

作　　者：王军 任岩岩[2] WANG Jun;REN Yanyan(Department of Anesthesiology,Luoyang Hospital of Traditional Chinese Medicine,Luoyang,Henan 471000,China;Department of Anesthesiology,the First Affiliated Hospital of Henan University of Science and Technology,Luoyang,Henan 471000,China)

机构地区：[1]洛阳市中医院麻醉科,河南洛阳471000 [2]河南科技大学第一附属医院麻醉科,河南洛阳471000

出　　处：《中国医学工程》2022年第6期51-54,共4页China Medical Engineering

摘　　要：目的探讨比较基于舒芬太尼和芬太尼的静脉患者自控镇痛(IV-PCA)对腹腔镜肾切除术后恶心呕吐(PONV)的影响。方法选取2019至2020年于洛阳市中医院接受治疗的80名腹腔镜肾切除术后患者,依据随机抽签法分为观察组(舒芬太尼治疗)和对照组(芬太尼治疗),比较两组PONV发生率、Rhodes评分、止吐药物及止痛药的使用、不良事件及Ramsay镇静评分。结果两组PONV发生率、需要止吐药物患者总人数及Rhodes评分比较,差异均无统计学意义(P>0.05)。两组术后疼痛评分、静脉自控镇痛的使用剂量、夹住静脉自控镇痛的患者人数以及患者满意度评分比较,差异均无统计学意义(P>0.05)。两组术后排气时间、不良事件发生率和Ramsay镇静评分比较,差异均无统计学意义(P>0.05)。结论基于舒芬太尼和基于芬太尼的IV-PCA显示出相似的PONV发生率,并且在腹腔镜肾切除术后镇痛效果相当。基于这些结果,建议舒芬太尼和芬太尼对腹腔镜肾切除术后IV-PCA的疗效相当。【Objective】To compare the effects of sufentanil and fentanyl-based intravenous patient-controlled analgesia(IVPCA)on postoperative nausea and vomiting(PONV)after laparoscopic nephrectomy.【Methods】Eighty patients undergoing laparoscopic nephrectomy in our hospital from 2019 to 2020 were selected,and divided into observation group(sufentanyl treatment)and control group(fentanyl treatment)according to the random drawing method,and the incidence of PONV,Rhodes score,use of antiemetic drugs and analgesics,adverse events,and Ramsay sedation score were compared between the two groups.【Results】There was no significant difference in the incidence of PONV,the total number of patients requiring antiemetic drugs and Rhodes score between the two groups(P>0.05).There was no significant difference between the two groups in postoperative pain score,cumulative dosage of patient-controlled intravenous analgesia,number of patients with clamped patient-controlled intravenous analgesia and patient satisfaction score(P>0.05).There was no significant difference in postoperative exhaust time,incidence of adverse events and Ramsay sedation score between the two groups(P>0.05).【Conclusion】Sufentanyl-based and fentanyl-based IV-PCA showed a similar incidence of PONV and had comparable analgesic effects after laparoscopic nephrectomy.Based on these results,we suggest that sufentanil and fentanyl are equally effective for IV-PCA after laparoscopic nephrectomy.

关 键 词：舒芬太尼 芬太尼 静脉患者自控镇痛 腹腔镜肾切除术 术后恶心和呕吐 

分 类 号：R614[医药卫生—麻醉学]