植物花青素对肿瘤抑制作用的研究进展  

Research progress in the inhibitory effects of plant anthocyanins on tumors

作　　者：于晓兰 刘艳(综述)[3] 刘家仁(审校)[1,2] YU Xiaolan;LIU Yan;LIU Jiaren(Department of Clinical Laboratory,The Forth Affiliated Hospital of Harbin Medical University,Harbin 150001,China;Heilongjiang Longwei Precision Medical Laboratory Center;Department of Oncology,The Forth Affiliated Hospital of Harbin Medical University)

机构地区：[1]哈尔滨医科大学附属第四医院检验科,哈尔滨150001 [2]黑龙江龙卫精准医学检验中心 [3]哈尔滨医科大学附属第四医院肿瘤科

出　　处：《实用肿瘤学杂志》2022年第3期245-249,共5页Practical Oncology Journal

基　　金：哈尔滨市重点科技攻关项目(编号:2021ZSZZNS02);黑龙江省应用技术研究与开发计划项目重大项目(编号:GA17C011);吴阶平医学基金会临床科研专项资助基金(编号:320.6750.2020-19-21)。

摘　　要：植物花青素是一类可溶于水的类黄酮,主要存在于各种蔬菜水果中。常见的植物花青素主要分为天竺葵色素(Pelargonidin)、芍药色素(Peonidin)、矢车菊色素(Cyanidin)、锦葵色素(Malvidin)、矮牵牛色素(Petunidin)、飞燕草色素(Delphinidin)六种;植物花青素分子中含有共轭双键体系,并含有碱性或酸性基团,因而具有抗氧化、抗炎、调节免疫、抗衰老和抑癌等生物学作用,尤其以抑癌作用最为突出。因此,本文将对植物花青素的抑癌作用及可能的机制进行综述。Plant anthocyanins are a class of water-soluble flavonoids,which mainly found in various vegetables and fruits.Common plant anthocyanins are mainly divided into six species including pelargonidin,peonidin,cyanidin,malvidin,petunidin,and delphinidin;Because the phytocyanin molecules contain conjugated double bond systems with basic or acidic groups,they have biological effects such as anti-oxidation,anti-inflammation,immune regulation,anti-aging,and anti-cancer,especially for inhibitory effects of tumor.Therefore,this article will review tumor suppressive effects and possible mechanisms of plant anthocyanins.

关 键 词：植物花青素 抑癌作用 机制 

分 类 号：R282.71[医药卫生—中药学]