早期新生儿灌注指数与疾病严重程度的相关性研究  

Correlation between perfusion index and the severity of disease in early neonates

作　　者：刘雪琴 张卫星 沈洁 刘玉霞 唐成和[2] Liu Xueqin;Zhang Weixing;Shen Jie;Liu Yuxia;Tang Chenghe(Xinxiang Central Hospital,the Fourth Clinical College of Xinxiang Medical College,Xinxiang 453000,China;Department of Neonatology,the First Affiliated Hospital of Xinxiang Medical College,Xinxiang 453100,China)

机构地区：[1]新乡市中心医院新乡医学院第四临床学院,453000 [2]新乡医学院第一附属医院新生儿科,453100

出　　处：《中国小儿急救医学》2022年第4期288-291,共4页Chinese Pediatric Emergency Medicine

摘　　要：目的分析灌注指数(PI)在评估新生儿病情严重程度中的作用。方法选择2018年10月至2019年7月新乡市中心医院出生后24 h内入住新生儿科的新生儿502例。入院后24 h内进行新生儿危重病例评分(NCIS),NCIS>90分为非危重,NCIS 70~90分为危重,NCIS<70分为极危重。所有入组新生儿在出生后24 h内安静状态下应用脉搏血氧仪监测PI值。其中非危重341例,危重110例,极危重51例。结果非危重组、危重组和极危重组患儿的PI值[M(P25,P75)]分别为1.80(1.40,2.60)、0.96(0.74,1.43)、0.65(0.41,1.10),3组间比较差异有统计学意义(P<0.05)。足月儿组、中/晚期早产儿组、极/超早产儿组PI值分别为1.70(1.20,2.70)、1.60(1.10,2.30)、1.35(0.80,2.30),3组间比较差异有统计学意义(P<0.05)。PI与NCIS呈中度正相关(r=0.791,P<0.01)。以PI值预测NCIS的受试者工作特征曲线下面积为0.846,以PI=0.56为截断值时,敏感度为85.0%,特异度为70.8%。结论PI与NCIS相关性高,可以反映新生儿疾病的严重程度,PI值越低,病情越重。Objective To analyze the role of perfusion index(PI)in assessing the severity of neonatal illnesses.Methods A total of 502 newborns admitted to the Department of Neonatology within 24 hours of birth at Xinxiang Central Hospital from October 2018 to July 2019 were recruited.Neonatal critical illness score(NCIS)was graded within 24 hours of admission,and newborns were categorized into non-critical(NCIS>90 scores),critical(NCIS 70-90 scores)and extremely critical(NCIS<70 scores).PI was monitored in all newborns within 24 hours of birth in a resting state.A total of 502 PIs were recorded,including 341 cases of non-critical,110 cases of critical and 51 cases of extremely critical.Results The medium PI[M(P25,P75)]of newborns in non-critical,critical and extremely critical groups were 1.80(1.40,2.60),0.96(0.74,1.43)and 0.65(0.41,1.10),respectively.PI values in extremely critical group was significantly lower than those in critical group and non-critical group(P<0.05).The medium PI[M(P25,P75)]of full-term newborns,moderate/late preterm newborns and extremely/very preterm newborns were 1.70(1.20,2.70),1.60(1.10,2.30)and 1.35(0.80,2.30),respectively.PI in full-term newborns was significantly higher than those in moderate/late preterm newborns and extremely/very preterm newborns(P<0.05).PI was moderately positively correlated with NCIS in newborns(r=0.791,P<0.01).The area under the receiver operating characteristic curve of NCIS predicted by PI value was 0.846,and the prediction sensitivity and specificity were 85.0%and 70.8%when PI was 0.56.Conclusion PI is correlated with NCIS in newborns,which is able to reflect the severity of neonatal illnesses.A low PI indicates severe conditions of neonatal illnesses.

关 键 词：灌注指数 早期新生儿 新生儿重症监护室 新生儿危重病例评分 

分 类 号：R722.1[医药卫生—儿科]