Fluorescent MOF-based nanozymes for discrimination of phenylenediamine isomers and ratiometric sensing of o-phenylenediamine  

作　　者：Yinghui Xia Kunming Sun Ya-Nan Zuo Shuyun Zhu Xian-En Zhao 

机构地区：[1]School of Chemistry and Chemical Engineering,Qufu Normal University,Qufu 273165,China

出　　处：《Chinese Chemical Letters》2022年第4期2081-2085,共5页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China (No. 22076097);the Natural Science Foundation of Shandong Province (No. ZR2020MB066)。

摘　　要：Although peroxidase-like nanozymes have made great progress in bioanalysis,few current nanozymebased biosensors are constructed for discriminating isomers of organic compounds.Herein,fluorescent metal-organic framework(MOF)-based nanozyme is utilized for phenylenediamine isomers discrimination and detection.NH_(2)-MIL-101(Fe),as a member of Fe-based MOFs,functions as not only fluorescent indicator but also peroxidase mimics.In the presence of H_(2)O_(2),NH2-MIL-101(Fe) can catalyze the oxidation of o-phenylenediamine(OPD) and p-phenylenediamine(PPD) into their corresponding oxidation products(OPDox and PPDox),which in turn quench its intrinsic fluorescence at 445 nm via inner filter effect(IFE).Differently,a new fluorescence peak at 574 nm is observed for OPDox.Thus,a ratiometric fluorescence method for the detection of OPD can be designed with the fluorescence intensity ratio F_(574)/F_(445)as readout.This proposed strategy displays excellent discrimination ability for three phenylenediamines and may open new applications of MOFs in environmental science.

关 键 词：Bifunctional MOF Nanozyme Photoluminescence Aromatic diamine isomers Ratiometric fluorescence 

分 类 号：O657.3[理学—分析化学] O625.631[理学—化学]