负荷心肌灌注显像中心率和血压变化预测女性心血管事件的研究进展  

Research progress of heart rate and blood pressure changes in stress myocardial perfusion imaging for predicting female cardiovascular events

作　　者：肖钰昕 武萍[1] 赵宇婷 李思进[1] Xiao Yuxin;Wu Ping;Zhao Yuting;Li Sijin(Department of Nuclear Medicine,First Hospital of Shanxi Medical University,Taiyuan 030001,China)

机构地区：[1]山西医科大学第一医院核医学科,太原030001

出　　处：《国际放射医学核医学杂志》2022年第3期152-156,共5页International Journal of Radiation Medicine and Nuclear Medicine

基　　金：国家自然科学基金(82001873)。

摘　　要：女性相比男性具有不同的冠状动脉(冠脉)解剖生理基础及神经激素水平,这导致其更多表现为非阻塞性冠脉微循环功能障碍。核素心肌灌注显像(MPI)血流绝对定量技术是一种无创性诊断冠心病(CAD)并对其进行风险评估的功能性检查方法。负荷试验中的心率和血压变化作为自主神经功能的替代指标,对女性血流灌注参数乃至不良心血管事件有一定的预测作用。笔者就负荷MPI中心率和血压变化对CAD诊断及风险评估的增益价值进行综述,为推进负荷MPI的临床应用及制定用以改善女性自主神经功能为靶点的诊疗方案提供依据。Compared with men,women have different anatomical and physiological basis of coronary artery and neurohormone levels,resulting in more often from non-obstructive coronary microvascular dysfunction.Absolute quantitative myocardial perfusion imaging(MPI)is a noninvasive functional examination,which increases diagnosis performance,treatment evaluation,and prognostic evaluation of coronary artery disease(CAD).The change of heart rate and blood pressure in stress test,as the alternative indicator of autonomic nerve function,has a role in predicting blood perfusion parameters and adverse cardiovascular events.This review summarizes the gain value of stress MPI heart rate and blood pressure change on CAD diagnosis and risk assessment,so as to provide a basis for promoting the clinical application of stress MPI and formulating a diagnosis and treatment plan aimed to improving female autonomic nerve function.

关 键 词：心率 血压 负荷心肌灌注显像 冠脉血流储备 心肌血流量 女性 

分 类 号：R54[医药卫生—心血管疾病]