左颞部非典型性纤维黄瘤一例  

A case of atypical fibroxanthoma on the left temporal

作　　者：王欢 王春又 杨海潮 邓向芬 张恋 翟志芳 WANG Huan;WANG Chun-you;YANG Hai-chao(Department of Dermatology,the First Affiliated Hospital of Army Military Medical University,Chongqin 400038,China)

机构地区：[1]陆军军医大学第一附属医院皮肤科,重庆400038

出　　处：《实用皮肤病学杂志》2022年第2期121-123,共3页Journal of Practical Dermatology

摘　　要：84岁女性患者,因左侧颞部暗红色结节6个月余就诊。皮肤科情况:左侧面颞部2 cm×2.5 cm类圆形隆起性暗红色肿物,表面光滑,可见毛细血管扩张,中央约豌豆大小溃疡,表面覆黑褐色痂,质中。组织病理检查示:表皮萎缩变薄,真皮上部胶原变性,真皮内大量组织样细胞、梭形细胞、多角形细胞及多核巨细胞浸润,部分细胞核大深染,明显多形性。免疫组化染色示:CD10、CD99、Vimentin、CD68阳性,Ki-67约60%阳性,S-100散在阳性,CK、CEA、EMA、BerEP4、D2-40、ERG、CD34肿瘤细胞均阴性。诊断:非典型性纤维黄瘤。An 84-year-old female patient had a dark red gradually enlarged nodule on the left side of the temple for more than half a year,with mild itching.Physical examination showed there was a dark red suborbicular raised mass about 2 cm×2.5 cm in size on the left lateral temporal,with a pea-sized ulcer in the middle of the mass and a smooth surface and obvious telangiectasia around the ulcer.Histopathology showed the atrophy and thinning epidermis,collagen degeneration in the upper dermis,and a large number of histiocytes,spindle cells,polygonal cells,and multinucleated giant cells infiltrated the dermis,and some of the nuclei were large and deeply stained with obvious pleomorphism.Immunohistochemical results showed that CD 10,CD99,Vimentin and CD68 were positive,about 60%were postive for Ki-67,S-100 was scattered positive,CK,CEA,EMA,BerEP4,D2-40,ERG and CD34 were all negative for tumor cells.Combined with the clinical manifestations,it was diagnosed as atypical fibroxanthoma.

关 键 词：纤维黄瘤 非典型性 

分 类 号：R758.7[医药卫生—皮肤病学与性病学]