针刺治疗围绝经期早醒型失眠:随机对照试验  

Acupuncture for perimenopausal early-wake insomnia:a randomized controlled trial

作　　者：诸剑芳[1] 刘涛[1] 胡芬 盛吉莅 金园园[1] ZHU Jian-fang;LIU Tao;HU Fen;SHENG Ji-li;JIN Yuan-yuan(Department of Acupuncture and Moxibustion,Zhejiang Hospital,Hangzhou 310013,China;Second Clinical Medical College,Zhejiang Chinese Medical University,Hangzhou 310053)

机构地区：[1]浙江医院针灸科,杭州310013 [2]浙江中医药大学第二临床医学院,杭州310053

出　　处：《中国针灸》2022年第6期608-612,共5页Chinese Acupuncture & Moxibustion

基　　金：金肖青名老中医专家传承工作室项目:GZS2021011;浙江中医药科技计划项目:2019ZB001、2019ZQ001。

摘　　要：目的:观察针刺治疗围绝经期早醒型失眠的临床疗效。方法:将60例围绝经期早醒型失眠患者随机分为观察组(30例,脱落3例)和对照组(30例,脱落2例、剔除2例)。观察组予针刺治疗,穴取百会、印堂、安眠、合谷、神门、太冲、太溪等,隔日1次,每周3次;对照组予谷维素片口服,每次20 mg,每日3次,两组均治疗4周。采用睡眠体动记录仪(ACT)检测两组患者治疗前后有效睡眠时间、睡眠质量、觉醒时间、觉醒次数、每次觉醒时间,比较两组患者治疗前后匹兹堡睡眠质量指数(PSQI)评分及早醒评分,并评定临床疗效。结果:与治疗前比较,治疗后观察组有效睡眠时间延长、睡眠质量升高(P<0.05),觉醒时间及每次觉醒时间缩短、觉醒次数减少(P<0.05),PSQI评分、早醒评分降低(P<0.05);对照组觉醒次数减少、PSQI评分及早醒评分降低(P<0.05)。治疗后,观察组有效睡眠时间、睡眠质量、觉醒时间、觉醒次数、每次觉醒时间及PSQI评分、早醒评分均优于对照组(P<0.05)。观察组总有效率为88.9%(24/27),高于对照组的38.5%(10/26,P<0.05)。结论:针刺治疗可增加围绝经期早醒型失眠患者有效睡眠时间,提高睡眠质量。Objective To observe the clinical effect of acupuncture for perimenopausal early-wake insomnia.Methods A total of 60 patients with perimenopausal early-wake insomnia were randomly divided into an observation group(30 cases,3 cases dropped off)and a control group(30 cases,2 cases dropped off,2 cases were removed).In the observation group,acupuncture was applied at Baihui(GV 20),Yintang(GV 24+),Anmian(Extra),Hegu(LI 4),Shenmen(HT 7),Taichong(LR 3),Taixi(KI 3),etc.,once every other day,3 times a week.In the control group,oryzanol tablets were taken orally,20 mg each time,3 times a day.Both groups were treated for 4 weeks.Before and after treatment,the sleep actigraphy(ACT)was used to measure the effective sleep time,sleep quality,wake-up time,wake-up frequency,each wake-up time,and the Pittsburgh sleep quality index(PSQI)score and early-wake score were compared in the two groups,and the clinical effect was assessed.Results After treatment,compared before treatment,the effective sleep time was prolonged and the sleep quality was improved(P<0.05),the wake-up time,each wake-up time were shortened and wake-up frequency was decreased(P<0.05),the PSQI score and early-wake score were decreased(P<0.05)in the observation group.After treatment,the wake-up frequency,PSQI score and early-wake score were decreased in the control group(P<0.05).The effective sleep time,sleep quality,wake-up time,wake-up frequency,each wake-up time,PSQI score and early-wake score after treatment in the observation group were superior to the control group(P<0.05).The total effective rate was 88.9%(24/27)in the observation group,which was higher than 38.5%(10/26)in the control group(P<0.05).Conclusion Acupuncture can increase the effective sleep time and improve sleep quality in patients with perimenopausal early-wake insomnia.

关 键 词：围绝经期早醒型失眠 针刺 睡眠体动记录仪 睡眠-觉醒状态 匹兹堡睡眠质量指数(PSQI) 

分 类 号：R246.3[医药卫生—针灸推拿学]