5-异戊烯基紫铆花素的全合成研究  

Total synthesis of 5-prenylbutein

作　　者：赵艳敏[1] 李红俊 ZHAO Yan-min;LI Hong-jun(Department of Chemical and Biological Engineering,Yinchuan Institute of Energy,Yinchuan 750105,China;NingXia Academy of Metrology and Quality Inspection,Yinchuan 750411,China)

机构地区：[1]银川能源学院化学与生物工程学院,宁夏银川750105 [2]宁夏计量质量检验检测研究院,宁夏银川750411

出　　处：《化学研究与应用》2022年第6期1448-1451,共4页Chemical Research and Application

基　　金：宁夏自然科学基金项目(2020AAC03275)资助。

摘　　要：以廉价的3,4-二羟基苯甲醛和2,4-二羟基苯乙酮为起始原料,经过C-异戊烯基化,酚羟基保护,羟醛缩合和去保护基等步骤,以32%的总收率完成了天然产物5-异戊烯基紫铆花素的全合成。所有新化合物的结构都经过^(1)H NMR、IR、MS确认。The total synthesis of the natural product 5-isopentenyl purpureol was achieved in an overall yield of 37%,by using cheap 3,4-dihydroxybenzaldehyde and 2,4-dihydroxyacetophenone as starting materials,and going through C-prenylation,phenolic hydroxyl protection,hydroxyl aldol condensation and protecting group removal.The structures of all the new compounds were confirmed by their 1H NMR,IR and MS spectra.

关 键 词：紫铆花素 异戊烯基 全合成 

分 类 号：O625.1[理学—有机化学]