电针足三里及上巨虚治疗术后肠麻痹的效果及对炎症反应的影响  

Effect of electroacupuncture at Zusanli and Shangjuxu on postoperative ileus and its influence on inflammation response

作　　者：喻敏 杨先玉[2] 陈盼敏 郑慧华[2] 李群 YU Min;YANG Xianyu;CHEN Panmin;ZHENG Huihua;LI Qun(College of Clinical Medicine,Jiangxi University of Traditional Chinese Medicine,Jiangxi Province,Nanchang 330006,China;Department of General Surgery,Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine,Jiangxi Province,Nanchang 330006,China)

机构地区：[1]江西中医药大学临床医学院,江西南昌330006 [2]江西中医药大学附属医院普外科,江西南昌330006

出　　处：《中国医药导报》2022年第16期135-138,160,共5页China Medical Herald

基　　金：江西省中医药科研课题(2019A352)。

摘　　要：目的探讨电针足三里及上巨虚对腹部术后肠麻痹的效果及对炎症反应的影响。方法选取2020年1月至2021年7月江西中医药大学附属医院收治的50例腹部术后肠麻痹患者,采用随机数字表法将其分为对照组(术后常规治疗,25例)和电针组(电针足三里及上巨虚联合常规治疗,25例)。两组均治疗7 d。比较两组临床疗效、胃肠功能恢复情况(肠鸣音恢复时间、首次排气排便时间、进食时间),并比较术前1 d、术后1 d和术后7 d的血清炎症因子(肿瘤坏死因子-α、白细胞介素-6、C反应蛋白)水平,观察不良反应情况。结果两组临床疗效比较,差异无统计学意义(P>0.05)。电针组肠鸣音恢复时间、首次排气、排便时间及进食时间均明显短于对照组,差异有统计学意义(P<0.05)。整体分析发现,组间比较、时间点比较及交互作用,差异均有统计学意义(P<0.05)。组内比较:两组术后7 d血清肿瘤坏死因子-α、白细胞介素-6、C反应蛋白水平均低于术前和术后1 d,差异有统计学意义(P<0.05);组间比较:电针组术后7 d血清肿瘤坏死因子-α、白细胞介素-6、C反应蛋白水平低于对照组,差异有统计学意义(P<0.05)。两组治疗期间均未出现不良反应。结论电针足三里和上巨虚可以有效促进术后肠麻痹患者胃肠功能恢复,减轻机体炎症反应,且安全性好。Objective To observe the effect of electroacupuncture at Zusanli and Shangjuxu on postoperative ileus after abdominal surgery and its influence on inflammation.Methods A total of 50 patients with postoperative ileus after abdominal surgery admitted to Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine from January 2020 to July 2021 were selected,and the patients were divided into control group(conventional postoperative treatments,25 cases)and electroacupuncture group(electroacupuncture at Zusanli and Shangjuxu combined with conventional postoperative treatments,25 cases)by the random number table method.Both groups were treated for seven days.The clinical efficacy and the recovery situation of gastrointestinal function(bowel sound recovery time,first exhaust and defecation time,and eating time)were compared between the two groups,and the levels of serum inflammatory factors(tumor necrosis factor-α,interleukin-6,and C reaction protein)were compared on one day before operation,one day and seven days after operation,and the adverse reaction was observed.Results There was no significant difference in clinical efficacy between the two groups(P>0.05).Bowel sound recovery time,first exhaust time,defecation time,and eating time in electroacupuncture group were significantly shorter than those in the control group,the differences were statistically significant(P<0.05).The overall analysis showed that there were statistically significant differences between groups,time points,and interactions(P<0.05).Intra-group comparison:serum tumor necrosis factor-α,interleukin-6,and C reaction protein levels at seven days after operation were lower than those before operation and one day after operation,the differences were statistically significant(P<0.05);comparison among groups:the levels of serum tumor necrosis factor-α,interleukin-6,and C reaction protein in the electroacupuncture group were lower than those in the control group at seven days after operation,the differences were statistically significant

关 键 词：电针 足三里 上巨虚 术后肠麻痹 胃肠功能 

分 类 号：R246.2[医药卫生—针灸推拿学]