良性前列腺增生并发下尿路症状的影响因素分析  

Analysis of the influencing factors of benign prostatic hyperplasia complicated with lower urinary tract symptoms

作　　者：徐赟峰 尤志新 李亦磊 邱峰[2] XU Yunfeng;YOU Zhixin;LI Yilei;QIU Feng(Department of Urology,Kunshan Second Hospital,Jiangsu Province,Kunshan 215300,China;Department of Urology,the First Affiliated Hospital of Soochow University,Jiangsu Province,Suzhou 215000,China)

机构地区：[1]江苏省昆山市第二人医院泌尿外科,江苏昆山215300 [2]苏州大学附属第一医院泌尿外科,江苏苏州215000

出　　处：《中国医药导报》2022年第18期71-74,共4页China Medical Herald

基　　金：江苏省高层次卫生人才“六个一工程”拔尖人才科研项目(LGY2019085)。

摘　　要：目的分析良性前列腺增生并发下尿路症状的影响因素。方法回顾性分析2018年5月至2020年4月苏州大学附属第一医院收治的124例良性前列腺增生并发下尿路症状患者(研究组)与133例良性前列腺增生未并发下尿路症状患者(对照组)的临床资料。采用国际前列腺症状评分(IPSS)按照病情的严重程度将研究组记为轻度组(48例,IPSS 0~7分),中度组(54例,IPSS 8~19分),重度组(22例,IPSS 20~35分)。采用logistic回归分析探讨良性前列腺增生患者并发重度下尿路症状的影响因素。结果研究组收缩压、舒张压、体重指数(BMI)、前列腺体积(PV)、空腹血糖(FBG)高于对照组,腰围、臀围低于对照组,差异有高度统计学意义(P<0.01)。三组BMI、腰臀比(WHR)、PV比较,差异有高度统计学意义(P<0.05)。进一步两两比较显示,重度组BMI、WHR、PV高于轻度、中度组,差异有统计学意义(P<0.05);中度组BMI、WHR、PV高于轻度组,差异有统计学意义(P<0.05)。重度组WHR、PV、BMI水平高于轻中度组,合并下尿路感染比例高于轻中度组,差异有统计学意义(P<0.05)。logistic多因素回归分析显示,WHR(OR=3.077)、PV(OR=3.838)、BMI(OR=2.724)为良性前列腺增生患者并发重度下尿路症状的影响因素(P<0.05)。结论WHR、PV、BMI为良性前列腺增生患者并发下尿路症状患者的危险因素。Objective To analyze the influencing factors of benign prostatic hyperplasia complicated with lower urinary tract symptoms.Methods The clinical data of patients admitted to the First Affiliated Hospital of Soochow University from May 2018 to April 2020 which were included 124 patients with benign prostatic hyperplasia complicated with lower urinary tract symptoms(study group)and 133 patients with benign prostatic hyperplasia without lower urinary tract symptoms(control group)were retrospectively analyzed.Using the international prostate symptom score(IPSS),the patients in the study group were recorded as mild group(48 cases,IPSS 0-7 points),moderate group(54 cases,IPSS 8-19 points),and severe group(22 cases,IPSS 20-35 points)according to the severity of the disease.Logistic regression analysis was used to explore the influencing factors of severe lower urinary tract symptoms in patients with benign prostatic hyperplasia.Results The systolic blood pressure,diastolic blood pressure,body mass index(BMI),prostate volume(PV),and fasting blood glucose(FBG)in the study group were higher than those in the control group,while waist circumference and hip circumference were lower than those in the control group,and the differences were highly statistically significant(P<0.01).There were highly statistically significant differences in BMI,waist-to-hip ratio(WHR),and PV among the three groups(P<0.05).Further pairwise comparison showed that the severe group had higher BMI,WHR,and PV than those of the mild and moderate groups,and the differences were statistically significant(P<0.05);the BMI,WHR,and PV of the moderate group were higher than those of the mild group,and the differences were statistically significant(P<0.05).The levels of WHR,PV,and BMI in the severe group were higher than those in the mild-moderate group,while the proportion of combined lower urinary tract infection was higher than that in the mild-moderate group,and the differences were statistically significant(P<0.05).Logistic multivariate regression analysis

关 键 词：良性前列腺增生 下尿路症状 影响因素 

分 类 号：R697.3[医药卫生—泌尿科学]