基于多巴胺氧化聚合制备电荷相反纳米磁的研究  

Preparation of oppositely charged nanomagnets based on oxidative polymerization of dopamine

作　　者：孟小琪 温暖 张伟[1] 左芳[1] MENG Xiao-qi;WEN Nuan;ZHANG Wei;ZUO Fang(School of Chemistry&Environment,Southwest Minzu University,Chengdu 610041,China)

机构地区：[1]西南民族大学化学与环境学院,四川成都610041

出　　处：《现代化工》2022年第6期118-123,共6页Modern Chemical Industry

基　　金：国家自然科学基金面上项目(51273220);西南民族大学研究生创新型科研项目(CX2020SZ14)。

摘　　要：采用不同氧化条件对油/水溶性纳米磁进行聚多巴胺(PDA)功能化,合成了Fe_(3)O_(4)@PDA-NaIO_(4)和Fe_(3)O_(4)@PDA。通过对其进行一系列表征发现,Fe_(3)O_(4)@PDA-NaIO_(4)和Fe_(3)O_(4)@PDA均具有较好的分散性,在pH 7.0下带相反电荷(+29.9 mV和-26.3 mV);两者饱和磁化强度分别为48.80 emu/g和62.11 emu/g,磁性能良好,且均具有超顺磁性。合成的PDA功能化纳米磁有望应用于核磁共振成像、靶向药物递送等生物医学领域。Fe_(3)O_(4)@PDA-NaIO_(4)and Fe_(3)O_(4)@PDA are synthesized through functionalizing oil/water soluble magnetic nanoparticles by polydopamine(PDA)under different oxidation conditions.Through a series of characterizations,it is found that both Fe_(3)O_(4)@PDA-NaIO_(4)and Fe_(3)O_(4)@PDA exhibit good dispersion and carry opposite charges at pH=7.0(+29.9 mV and-26.3 mV),which is due to the different compositional structures of PDA on both surfaces.In addition,the saturation magnetization intensity of these two particles is 48.80 emu·g^(-1)and 62.11 emu·g^(-1),respectively,both showing superparamagnetic.In conclusion,the synthesized PDA-functionalized magnetic nanoparticles are expected to be applied in biomedical fields such as nuclear magnetic resonance imaging and targeted drug delivery.

关 键 词：多巴胺 功能化改性 相反电荷 超顺磁性 纳米磁 

分 类 号：TB383.1[一般工业技术—材料科学与工程]