SAPHO综合征合并溃疡性结肠炎一例  

SAPHO Syndrome Complicated with Ulcerative Colitis:Report of One Case

作　　者：谢映菡 尤艳 李月婷 刘爽[3] 李丽[4] 赖雅敏[5] 杨红[5] 钱家鸣[5] XIE Yinghan;YOU Yan;LI Yueting;LIU Shuang;LI Li;LAI Yamin;YANG Hong;QIAN Jiaming(School of Clinical Medicine,CAMS and PUMC,Beijing 100730,China;Department of Pathology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China;Department of Allergy and Clinical Immunology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China;Department of Dermatology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China;Department of Gastroenterology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China)

机构地区：[1]中国医学科学院,北京协和医学院,临床医学部,北京100730 [2]中国医学科学院,北京协和医学院,北京协和医院变态反应科,北京100730 [3]中国医学科学院,北京协和医学院,北京协和医院病理科,北京100730 [4]中国医学科学院,北京协和医学院,北京协和医院皮肤科,北京100730 [5]中国医学科学院,北京协和医学院,北京协和医院消化内科,北京100730

出　　处：《中国医学科学院学报》2022年第3期535-539,共5页Acta Academiae Medicinae Sinicae

基　　金：中国医学科学院医学与健康科技创新工程项目(2016-12M-3-001、2019-I2M-2-007)。

摘　　要：滑膜炎、痤疮、脓疱病、骨肥厚、骨炎(SAPHO)综合征是一种罕见病,既往文献报道约有10%的患者会合并炎症性肠病。迄今为止,国内罕有SAPHO综合征合并炎症性肠病的病例报告。本文报道1例SAPHO综合征合并溃疡性结肠炎的患者,该患者在SAPHO综合征病情活动期间行依那西普治疗缓解后出现结肠病变的复发。Synovitis,acne,pustulosis,hyperostosis,and osteitis(SAPHO)syndrome is a rare disease.The previous literature demonstrated that about 10%of the patients with SAPHO syndrome were complicated with inflammatory bowel disease.So far,few cases of SAPHO syndrome complicated with inflammatory bowel disease have been reported in China.Herein,we reported a SAPHO syndrome case complicated with ulcerative colitis.The patient suffered from recurrent attacks of colitis following treatment of SAPHO syndrome with etanercept.

关 键 词：SAPHO综合征 溃疡性结肠炎 依那西普 

分 类 号：R593[医药卫生—内科学]