抗菌药物不良反应及重要脏器损伤的判断  

Adverse reaction of antibacterial drugs and evaluation of vital organ injuries

作　　者：闫钢风 张俊琦 王一雪 陆国平 Yan Gangfeng;Zhang Junqi;Wang Yixue;Lu Guoping(Department of Pediatric Critical Care Medicine,Children′s Hospital of Fudan University,National Children′s Medical Center,Shanghai 201102,China;Department of Pharmacy,Children′s Hospital of Fudan University,National Children′s Medical Center,Shanghai 201102,China)

机构地区：[1]复旦大学附属儿科医院重症医学科,上海201102 [2]复旦大学附属儿科医院临床药学部,上海201102

出　　处：《中国小儿急救医学》2022年第5期326-329,共4页Chinese Pediatric Emergency Medicine

基　　金：国家重点研发计划(2021YFC2701800、2021YFC2701803)。

摘　　要：感染性疾病是临床较为常见的疾病种类,其中以细菌感染最为多见,因此,抗菌药物也成为临床应用最广泛的药物之一。而抗菌药物在挽救感染患者生命的同时,也会导致不良反应,严重时可造成脏器功能损伤,甚至危及生命。常见的不良反应包括过敏反应及各种脏器损害等。本文对抗菌药物引起的常见不良反应以及重要脏器损伤的评估进行综述,旨在加强抗菌药物不良反应的防治,促进临床合理用药。Infectious diseases are clinically very common,among which bacterial infections are the most common ones.Therefore,antibiotics have become ones of the most widely used drugs in clinical practice.While saving lives of many infected patients,antibiotics can also lead to adverse reactions,which can cause damage to organs function in severe cases and even life-threatening.Common adverse reactions include allergic reactions and various organs damage.In this review,we aimed to focus on the evaluation of common adverse reactions and organs damage caused by antibiotics,in order to improve the prevention and treatment of adverse reactions and promote rational use of antibiotics.

关 键 词：抗菌药物 不良反应 脏器功能损害 评估 

分 类 号：R978.1[医药卫生—药品]