残余胆固醇预测动脉粥样硬化性心血管疾病的研究进展  

Remnant Cholesterol in Predicting Atherosclerotic Cardiovascular Disease

作　　者：陈林滔 田清平[1] 刘梅林[1] CHEN Lintao;TIAN Qingping;LIU Meilin(Department of Geriatrics,Peking University First Hospital,Beijing 100034,China)

机构地区：[1]北京大学第一医院老年科,北京100034

出　　处：《心血管病学进展》2022年第6期492-494,共3页Advances in Cardiovascular Diseases

摘　　要：动脉粥样硬化性心血管疾病仍然是全球范围内发病率和死亡率最高的疾病,严重威胁着人类生命安全。其发病与脂质代谢紊乱关系密切,即使在引入降低胆固醇的药物治疗后,仍然存在归因于载脂蛋白B和脂蛋白a等的心血管残余风险,因此需要不断探索新的预防靶点。近些年越来越多的研究发现,除上述残余风险因素外,残余胆固醇在动脉粥样硬化性心血管疾病发病过程中扮演着越来越重要的预测作用。现关于残余胆固醇的最新研究做如下综述。Atherosclerotic cardiovascular disease is still the disease with the highest morbidity and mortality worldwide,which is closely associated with lipid metabolism disorder and seriously threatens the safety of human life.Even after the use of cholesterol-lowering drugs,there is still a residual cardiovascular risk attributed to apolipoprotein B and lipoprotein a.Therefore,it is necessary to constantly explore new prevention targets.In recent years,more and more studies have found that in addition to the above risk factors,remnant cholesterol plays an increasingly important role in predicting atherosclerotic cardiovascular disease.In this review,the latest research on remnant cholesterol is summarized as follows.

关 键 词：残余胆固醇 动脉粥样硬化性心血管疾病 脂质代谢 

分 类 号：R54[医药卫生—心血管疾病]