急性ST段抬高型心肌梗死患者微血管功能障碍的研究进展  

Microvascular Dysfunction in Patients with Acute ST-Segment Elevation Myocardial Infarction

作　　者：宋艳华 来春林[1] 杨五小 SONG Yanhua;LAI Chunlin;YANG Wuxiao(Department of Cardiovascular Medicine,The Fifth Clinical Medical College of Shanxi Medical University,Taiyuan 030012,Shanxi,China)

机构地区：[1]山西医科大学第五临床医学院心血管内科,山西太原030012

出　　处：《心血管病学进展》2022年第6期530-534,共5页Advances in Cardiovascular Diseases

摘　　要：急性ST段抬高型心肌梗死(STEMI)的治疗策略不断取得进展,但死亡率仍很高。经皮冠状动脉介入治疗后,心外膜冠状动脉循环恢复通畅,但部分患者仍存在心肌组织灌注不足,这种现象被称为无再流,其主要原因是严重的微血管功能障碍(MVD)。MVD是STEMI患者再灌注治疗后的一种重要病理改变,且总是与不良预后相关。因此对MVD的研究显得相当重要,现对STEMI患者MVD的相关研究做一综述。There has been continued advancement in treatment strategies for acute ST-segment elevation myocardial infarction(STEMI),however,the mortality of these patients remains high.After percutaneous coronary intervention,epicardial coronary artery circulation was restored,but some patients still had myocardial tissue insufficiency,a phenomenon known as no reperfusion,which is mainly due to severe microvascular dysfunction(MVD).MVD is an important pathological change after reperfusion therapy in patients with STEMI and always correlates with a poor prognosis.Therefore,it is very important to study MVD.This article reviews the research on MVD in STEMI patients.

关 键 词：ST段抬高型心肌梗死 经皮冠状动脉介入治疗 微血管功能障碍 微血管损伤 微循环阻力指数 

分 类 号：R54[医药卫生—心血管疾病]