酸催化基于环己二烯衍生物的转移氢化反应研究进展  

Progess of Acid-catalyzed Transfer Hydrogenation with Cyclohexadienes

作　　者：周新悦 王晓晨 ZHOU Xin-yue;WANG Xiao-chen(College of Chemistry,Nankai University,Tianjin 300071,China)

机构地区：[1]南开大学化学学院,天津300071

出　　处：《化学试剂》2022年第7期1012-1019,共8页Chemical Reagents

基　　金：国家自然科学基金项目(21871147)。

摘　　要：催化氢化反应是有机合成化学的一类重要反应,除直接使用氢气作为氢化试剂外,一些转移氢化试剂同样具有广泛的应用。环己二烯衍生物作为转移氢化试剂,与常见的转移氢化试剂Hantzsch酯相似,离去两个氢原子后可形成芳烃产物使体系的能量降低,同时离去的氢可以完成与不饱和底物的加成。对环己二烯衍生物参与的转移氢化反应进行综述,根据所使用的催化剂类型(有机硼路易斯酸、Br nsted酸以及金属路易斯酸)分类,简要介绍反应机理和底物适用性,并对反应创新性和局限性进行了总结。Catalytic hydrogenation is an important reaction in organic synthesis.In addition to direct hydrogenation using hydrogen gas,transfer hydrogenation also has a wide range of applications.As a class of transfer hydrogenation reagents,cyclohexadienes are similar to the commonly used Hantzsch esters.After elimination of two hydrogen atoms,aromaticity can be restored,which reduces the energy of the system,whereas the leaving hydrogen atoms can add to unsaturated bonds.In this paper,the transfer hydrogenation reactions involving cyclohexadienes are reviewed.According to the types of catalysts used(boron Lewis acids,Br nsted acids,and metal Lewis acids),their reaction mechanisms and substrate scopes are discussed.

关 键 词：催化氢化 转移氢化 酸催化 环己二烯 

分 类 号：O624.1[理学—有机化学]