维持性血液透析伴口干渴患者中医证型分布规律及相关性分析  

Distribution Rules and Correlation Analysis of Chinese Medicine Syndrome Types in Maintenance Hemodialysis Patients with Thirst

作　　者：王莉澜 张莎莎[1] 黄学锋 陆虎林 陈琪[1] WANG Lilan;ZHANG Shasha;HUANG Xuefeng;LU Hulin;CHEN Qi

机构地区：[1]湖州市第一人民医院中医科,浙江湖州313000

出　　处：《新中医》2022年第10期22-25,共4页New Chinese Medicine

基　　金：湖州市科技项目(2019GYB54)。

摘　　要：目的:观察100例长期维持性血液透析(MHD)伴口干渴患者中医证型的分布规律及相关因素。方法:选取临床不同证型的100例MHD伴口干渴患者,运用统计学方法,分析其中医证型的分布规律及其与性别,年龄,透析龄,口渴的视觉模拟评分法(VAS)、口腔干燥量表(XI)、透析口渴量表(DTI)评分,静息状态唾液流率,实验室指标血钾、血钠、血钙、血磷、甲状旁腺激素等的相关性。结果:MHD伴口干渴患者在证型分布上按比例由多到少依次为脾肾气阴两虚证68例,肝肾阴虚证21例,阴阳两虚证11例。其中,3种证型患者口干渴VAS评分、XI评分、DTI评分分别比较,脾肾气阴两虚证显著高于其他两型,差异均有统计学意义(P<0.05);以上指标肝肾阴虚证与阴阳两虚证间比较,差异均无统计学意义(P>0.05)。静息状态下唾液流率比较,脾肾气阴两虚证显著低于其他两证型,差异均有统计学意义(P<0.05);且肝肾阴虚证与阴阳两虚证组间比较,差异无统计学意义(P>0.05)。3种证型患者年龄、性别、透析龄、肌酐、尿素氮、血钾、血钙、血磷、甲状旁腺激素分别比较,差异均无统计学意义(P>0.05)。结论:维持性血液透析伴口干渴患者在中医证型的分布有一定的规律,以脾肾气阴两虚证为主,且口干渴程度较肝肾阴虚证及阴阳两虚证更甚,但与年龄、性别、透析龄及血钾、血钠、血钙、血磷、甲状旁腺激素无明显相关性。Objective:To observe the distribution rules and related factors of Chinese medicine syndrome types in100 cases of patients who were undergoing maintenance hemodialysis(MHD)for the long term and complicated with thirst.Methods:A total of 100 cases of patients with MHD and thirst with different clinical syndrome types were selected to analyze the distribution rules of Chinese medicine syndrome types and their correlation with gender,age,dialysis age,scores of Visual Analogue Scale(VAS),Xerostomia Inventory(XI)and Dialysis Thirst Inventory(DTI),salivary flow rate in resting state,blood potassium,blood sodium,blood calcium,blood phosphorus,parathyroid hormone and other laboratory indexes.Results:As for the distribution of syndrome types in MHD patients with thirst,there were 68 cases with spleen-kidney qiyin deficiency syndrome,21 cases with liver-kidney yin deficiency syndrome,and 11 cases with yin-yang deficiency syndrome;scores of VAS,XI and DTI in patients with spleen-kidney qi-yin deficiency syndrome were significantly higher than those with liver-kidney yin deficiency syndrome and with yin-yang deficiency syndrome,differences being significant(P<0.05);there was no significant difference being found in the comparisons of scores of VAS,XI and DTI between liverkidney yin deficiency syndrome and yin-yang deficiency syndrome(P>0.05).The salivary flow rate in resting state in the spleen-kidney qi-yin deficiency syndrome was significantly lower than those in liver-kidney yin deficiency syndrome and yinyang deficiency syndrome,differences being significant(P<0.05);there was no significant difference being found in the comparison of salivary flow rates between liver-kidney yin deficiency syndrome and yin-yang deficiency syndrome(P>0.05).There was no significant difference being found in the comparisons of age,sex,dialysis age,creatinine,urea nitrogen,blood potassium,blood calcium,blood phosphorus and parathyroid hormone among the three syndrome types(P>0.05).Conclusion:The distribution of Chinese medicine syndrome types

关 键 词：口干渴 维持性血液透析 慢性肾功能衰竭 中医证型 分布规律 相关因素 

分 类 号：R692.5[医药卫生—泌尿科学]