温针灸联合克罗米芬治疗多囊卵巢综合征不孕症疗效观察及对性激素、排卵情况的影响  

Clinical Effect of Warm-Needling Moxibustion Combined with Clomiphene Citrate for Infertility with Polycystic Ovary Syndrome and Its Effect on Sex Hormones and Ovulation

作　　者：薛利凤[1] 苗玉新[1] XUE Lifeng;MIAO Yuxin

机构地区：[1]济源市人民医院针灸科,河南济源459000

出　　处：《新中医》2022年第10期164-167,共4页New Chinese Medicine

摘　　要：目的:观察温针灸联合克罗米芬治疗多囊卵巢综合征(PCOS)不孕症的临床疗效及其对患者性激素、排卵情况的影响。方法:选择80例PCOS不孕症患者,按数字奇偶法分为对照组和治疗组各40例。对照组给予克罗米芬治疗,治疗组在对照组的基础上给予温针灸治疗。治疗3个月经周期后,评估2组临床疗效、中医证候积分、血清性激素水平及排卵、妊娠情况。结果:治疗后,治疗组总有效率为87.50%,对照组为67.50%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组中医证候积分比较,差异无统计学意义(P>0.05);治疗后,2组中医证候积分较治疗前降低(P<0.05),且治疗组证候积分降低较对照组更显著(P<0.05)。治疗前,2组血清促卵泡生成素(FSH)、促黄体生成素(LH)、睾酮(T)水平比较,差异无统计学意义(P>0.05)。治疗后,2组血清LH、T水平均较治疗前下降(P<0.05),且治疗组LH、T水平均低于对照组(P<0.05);2组血清FSH水平较治疗前上升(P<0.05),且治疗组FSH水平高于对照组(P<0.05)。治疗后,治疗组排卵率、妊娠率分别为82.50%、42.50%,对照组分别为60.00%、20.00%,2组比较,差异均有统计学意义(P<0.05)。结论:温针灸辅助克罗米芬治疗PCOS不孕症疗效确切,可改善患者临床症状,调节性激素水平,提高排卵率及妊娠率。Objective:To observe the clinical effect of warm-needling moxibustion combined with clomiphene citrate for infertility with polycystic ovary syndrome(PCOS)and its effect on sex hormones and ovulation.Methods:A total of 80 cases of PCOS patients with infertility were divided into the control group and the treatment group according to odd-even number method,with 40 cases in each group.The control group was treated with clomiphene citrate,and the treatment group was given warm-needling moxibustion combined with clomiphene citrate.After treatment for three menstrual cycles,clinical effects,Chinese medicine syndrome scores,serum sex hormones levels,ovulation and pregnancy state were evaluated in the two groups.Results:After treatment,the total effective rate was 87.50%in the treatment group,and 67.50%in the control group,the difference being significant(P<0.05).Before treatment,there was no significant difference being found in the comparison of Chinese medicine symptom scores between the two groups(P>0.05).After treatment,Chinese medicine symptom scores in the two groups were significantly decreased when compared with those before treatment(P<0.05),and the decrease of scores in the treatment group was more significant than that in the control group(P<0.05).Before treatment,there was no significant difference being found in the comparison of levels of follicle-stimulating hormones(FSH),luteinizing hormone(LH),and testosterone(T)in serum between the two groups(P>0.05).After treatment,levels of LH and T in serum in the two groups were significantly decreased when compared with those before treatment(P<0.05),and the two levels in the treatment group were lower than those in the control group(P<0.05);levels of serum FSH in the two groups were increased when compared with those before treatment(P<0.05),and the FSH level in the treatment group was higher than that in the control group(P<0.05).After treatment,the ovulation rate and pregnancy rate in the treatment group were 82.50%and 42.50%respectively,and those in the contr

关 键 词：多囊卵巢综合征 不孕症 克罗米芬 温针灸 血清性激素 

分 类 号：R711.75[医药卫生—妇产科学] R246.3[医药卫生—临床医学]