超声造影定性和定量分析在甲状腺乳头状癌侧颈区淋巴结转移术前诊断中的价值  

The Value of Qualitative and Quantitative Analysis of Contrast-enhanced Ultrasound in the Preoperative Diagnosis of Lymph Node Metastasis in the Lateral Neck Region of Papillary Thyroid Cancer

作　　者：陆健斐[1] 章然[1] 李卓原 李思齐[1] 刘小艳[1] 夏要友[1] 卜锐[1] Lu Jianfei;Zhang Ran;Li Zhuoyuan;Li Siqi;Liu Xiaoyan;Xia Yaoyou;Bu Rui(Department of Ultrasound,The Second Affiliated Hospital of Kunming Medical university,Kunming 650101,China)

机构地区：[1]昆明医科大学第二附属医院超声科,昆明市650101

出　　处：《中国超声医学杂志》2022年第5期497-501,共5页Chinese Journal of Ultrasound in Medicine

基　　金：云南省科技厅-昆明医科大学应用基础研究联合专项面上项目[No.2019FE001(-068)];昆明医科大学第二附属医院院内科技计划项目(No.2018yk019)。

摘　　要：目的探讨超声造影(CEUS)定性分析与定量参数对甲状腺乳头状癌(PTC)侧颈区淋巴结转移的术前鉴别诊断价值。方法选取60例行PTC根治术及侧颈区淋巴结清扫术患者共68枚淋巴结,根据病理结果分为转移组和未转移组,分析2组淋巴结的CEUS定性特征和定量参数。结果2组淋巴结增强模式、增强类型、有无增强缺损及TIC的差异均有统计学意义(P<0.05);2组淋巴结周边区PI、TTP比较有统计学意义(P<0.05),转移组周边区PI显著高于未转移组,TTP显著低于未转移组;2组淋巴结周边区与中央区的差值△PI、△TTP比较差异均有统计学意义(P<0.05),未转移组中央区PI大于周边区,TTP小于周边区,转移组周边区PI大于中央区,TTP小于中央区。结论CEUS定性和定量分析对术前甲状腺癌侧颈区淋巴结转移的鉴别诊断可提供有价值的信息。Objective To investigate the value of qualitative analysis and quantitative parameters of contrast-enhanced ultrasound(CEUS)for the preoperative diagnosis of lymph node metastasis in the lateral neck region of papillary thyroid cancer(PTC).Methods A total of 68 lymph nodes were selected from 60 patients who underwent radical PTC and lymph node dissection in the lateral cervical region in our hospital and were divided into metastatic and non-metastatic groups according to the pathological results,and the qualitative characteristics and quantitative parameters of CEUS of the two groups were analyzed.Results There were significant differences in enhancement pattern,enhancement type,presence or absence of enhancement defect,and TIC between the two groups(P<0.05).The regional PI of the metastatic group was significant higher and the TTP was significant lower than that of the non-metastatic group.The peripheral and the central area of the two groups were statistically significant differences inΔPI andΔTTP(P<0.05).In the non-metastatic group,the PI of the central area was greater and the TTP was smaller than that of the peripheral area;The PI of the peripheral area of the metastasis group was greater and the TTP was smaller than the central area.Conclusions Qualitative and quantitative analysis of CEUS can provide valuable information for the preoperative differential diagnosis of lymph node metastasis in the lateral neck region of PTC.

关 键 词：超声造影 定量分析 甲状腺乳头状癌 

分 类 号：R445.1[医药卫生—影像医学与核医学] R736.1[医药卫生—诊断学]