二维斑点追踪技术对急性正加速度暴露后飞行员左室心肌功能的评估  

Evaluation of Left Ventricular Myocardial Function in Pilots After Acute Positive Acceleration Exposure by Two-dimensional Speckle Tracking Technique

作　　者：丁蔓妮 范校周 张龙方 刘禧 阴玮伟 杨明浩 姚克纯 Ding Manni;Fan Xiaozhou;Zhang Longfang;Liu Xi;Yin Weiwei;Yang Minghao;Yao Kechun(Air Force Medical Center,PL A,Beijing 100142,China;Tangdu Hosp让al,Air Force Medical University,Xi'an 710038,China)

机构地区：[1]空军特色医学中心,北京市100142 [2]空军军医大学唐都医院,西安市710038

出　　处：《中国超声医学杂志》2022年第5期521-524,共4页Chinese Journal of Ultrasound in Medicine

基　　金：空军军医大学效能提升重大问题科技攻关(No.2019ZTB05);全军后勤科研重点项目(No.BKJ20J005)。

摘　　要：目的 应用二维斑点追踪技术评估飞行员急性正加速度(+Gz)暴露后左室心肌功能的变化。方法 共纳入53例飞行员参与+6Gz载人离心机实验,采用常规联合二维斑点追踪技术评估飞行员急性+6Gz暴露前、后左室常规参数及左室各平面纵向应变参数的变化。结果 与静息状态相比,+6Gz暴露后飞行员的血压、心率升高(P<0.001);LVIDd、LVIDs、E/A、LVEDV、LVESV显著减低(P<0.05);SV、LVEF、LVFS、IVSd、LVPWd、心尖四腔收缩峰值应变(GLPS-A4C)无统计学意义(P>0.05);左室整体收缩峰值应变(GLPS-AVG)、心尖两腔收缩峰值应变(GLPS-A2C)、左室长轴收缩峰值应变(GLPS-LAX)绝对值显著减低,差异有统计学意义(P<0.05)。结论 二维斑点追踪技术能灵敏检测急性+Gz暴露后飞行员左室收缩功能的变化。Objective Two-dimensional speckle tracking technique was used to assess the changes of left ventricular myocardial function in pilots after acute positive acceleration(+Gz) exposure. Methods A total of 53 pilots were included in the +6 Gz human centrifuge test. The left ventricular routine parameters and left ventricular longitudinal strain parameters before and after acute +6 Gz exposure were evaluated by conventional echocardiography combined two-dimensional speckle tracking technique. Results Compared with resting state, the blood pressure and heart rate of pilots increased immediately after +6 Gz exposure(P<0.001). LVIDd, LVIDs, E/A,LVEDV,LVESV decreased significantly(P<0.05). There were no significant difference in SV,LVEF,LVFS,IVSd, LVPWd and apical four-chamber global systolic peak strain(GLPS-A4 C)(P>0.05). The absolute values of left ventricular global peak systolic strain(GLPS-AVG), apical two-chamber global peak systolic strain(GLPS-A2 C) and left ventricular long-axis peak systolic strain(GLPS-LAX) decreased(P<0.05). Conclusions Two-dimensional speckle tracking technique can sensitively detect the changes of left ventricular systolic function in pilots after acute +Gz exposure.

关 键 词：斑点追踪技术 左心室功能 载人离心机 正加速度 

分 类 号：R445.1[医药卫生—影像医学与核医学] R852.21[医药卫生—诊断学]