肺硬化性血管瘤12例临床特点分析  

Clinical characteristics of 12 cases of pulmonary sclerosing hemangioma

作　　者：李严平[1] 段新春 吴艳军[3] LI Yanping;DUAN Xinchun;WU Yanjun(Department of General Medicine,Daxing District People's Hospital of Beijing,Beijing 102600,China)

机构地区：[1]北京市大兴区人民医院全科医学科,102600 [2]首都医科大学附属北京友谊医院胸外科 [3]首都医科大学附属北京友谊医院呼吸内科

出　　处：《心肺血管病杂志》2022年第5期497-501,共5页Journal of Cardiovascular and Pulmonary Diseases

基　　金：北京市自然科学基金(7204247)。

摘　　要：目的:归纳和探讨肺硬化性血管瘤患者临床特点,提高临床医师对该疾病的诊疗认识。方法:回顾性收集首都医科大学附属北京友谊医院近5年肺硬化性血管瘤患者的基本情况,临床表现,影像学检查及病理检查等临床资料,分析和讨论该疾病的临床特点。结果:共收集临床资料完整的肺硬化性血管瘤患者12例,均为女性,平均年龄(51.42±12.38)岁,无吸烟史患者10例,均无肿瘤家族史。临床表现主要为咳嗽、咳痰及痰中带血。影像学表现肺结节10例,肿块2例,可表现为边缘光滑、规整,或者毛刺状、分叶状,可有钙化、胸膜牵拉,CT增强后可有强化。病理结果提示免疫组化EMA及TTF-1均阳性,术后随访均预后良好。结论:肺硬化性血管瘤临床少见,容易忽视,且临床表现及影像学特点不典型,与肺癌鉴别难度大,病理诊断是金标准,手术切除是唯一有效的治疗方案。Objective:To summarize and explore the clinical characteristics of patients with pulmonary sclerosing hemangioma and improve clinicians'understanding of the diagnosis and treatment of the disease.Methods:The basic information,clinical manifestations,imaging and pathological examination of pulmonary sclerosing hemangioma in Beijing Friendship Hospital Affiliated to Capital Medical University in recent 5 years were collected retrospectively,and the clinical characteristics of the disease were analyzed and discussed.Results:12 patients with pulmonary sclerosing hemangioma with complete clinical data were all female,and the average age was(51.42±12.38)years.There were 10 patients without smoking history and all patients had no family history of tumor.The main clinical manifestations were cough,expectoration and blood in sputum.Imaging findings were pulmonary nodules in 10 cases and masses in 2 cases,which could be characterized by smooth and regular edges,burr and lobulation,calcification,pleural traction and there was enhancement after enhanced CT scan.The pathological results showed that EMA and TTF-1 were positive by immunohistochemistry,and the prognosis was good after operation.with follow-up.Conclusions:Pulmonary sclerosing hemangioma is rare and easy to ignore,and its clinical manifestations and imaging characteristics are not typical.It is difficult to distinguish it from lung cancer.Pathological diagnosis is the gold standard,and surgical resection is the only effective treatment.

关 键 词：肺硬化性血管瘤 临床特点 肺癌 

分 类 号：R54[医药卫生—心血管疾病]