脑康Ⅱ号联合中药穴位敷贴对老年失眠病人睡眠质量和生活质量的影响  

Effect of NaokangⅡCombined with Acupoint Application on Sleep Quality and Life Quality in Aged Insomniac

作　　者：陈玉静[1] 黄小波[1] 王倩[1] 孙亚男[1] 刘妍[1] 吴犀翎[1] CHEN Yujing;HUANG Xiaobo;WANG Qian;SUN Yanan;LIU Yan;WU Xiling(Xuanwu Hospital Capital Medical University,Beijing Geriatric Institute of Integrated Traditional and Western Medicine,Beijing 100053,China)

机构地区：[1]首都医科大学宣武医院,北京市中西医结合老年疾病研究所,北京100053

出　　处：《中西医结合心脑血管病杂志》2022年第12期2156-2159,共4页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

基　　金：北京市中医药科技项目(No.JJ2018-22);北京市自然科学基金资助项目(No.7172094)。

摘　　要：目的观察脑康Ⅱ号联合中药穴位敷贴对肾虚精亏、痰瘀内阻型老年失眠病人睡眠质量和生活质量的影响。方法将180例失眠病人随机分为西药组、中药组和联合组,3组均治疗4周。观察3组临床疗效,分别应用匹兹堡睡眠质量指数量表(PSQI)评分、健康状况问卷(SF-36)量表和副反应量表(TESS)评定病人睡眠质量、生活质量和药物干预后出现的不良反应。结果西药组总有效率为73.3%,中药组总有效率为80.3%,联合组总有效率为96.6%,联合组和中药组总有效率优于西药组,且联合组优于中药组,差异有统计学意义(P<0.01)。治疗后,西药组PQSI评分较治疗前降低,差异有统计学意义(P<0.01);联合组PQSI的6个因子积分低于西药组,差异有统计学意义(P<0.01),联合组PQSI的6个因子积分低于中药组,差异有统计学意义(P<0.05)。治疗后,中药组和联合组SF-36各维度较治疗前均升高,差异有统计学意义(P<0.01)。西药组治疗后身体疼痛评分升高,差异有统计学意义(P<0.01);中药组和联合组躯体健康、社会功能、躯体角色、心理健康、情绪角色、精力及总体健康评分改善优于西药组,差异有统计学意义(P<0.01);联合组与中药组躯体健康、社会功能、精力和总体健康评分比较,差异有统计学意义(P<0.01)。与西药组比较,中药组和联合组行为毒性、自主神经系统症状、其他评分及总分均优于西药组,差异有统计学意义(P<0.01)。结论脑康Ⅱ号联合穴位敷贴能改善肾虚精亏、痰瘀内阻型老年失眠病人睡眠质量和生活质量。Objective To observe the effect of NaokangⅡcombined with acupoint application on sleep quality and life quality in aged insomniac with kidney deficiency and essence deficiency,and internal resistance of phlegm and blood stasis.Methods One hundred and eighty insomniac were randomly divided into western medicine group,traditional Chinese medicine group,and combined group,and they were treated for 4 weeks.The clinical efficacy of the three groups was observed,and the Pittsburgh Sleep Quality Index(PSQI)score,the Health Status Questionnaire(SF-36)and The Side Effects Scale(TESS)were used to evaluate the sleep quality,quality of life and adverse reactions after drug intervention.Results The clinical efficacy of the combination group(96.6%)and the traditional Chinese medicine group(80.3%)was better than that of the western medicine group(73.3%),and that of the combined group was better than that of the traditional Chinese medicine group(P<0.01).After treatment,the PQSI scores(sleep quality,time of falling asleep,sleep time,sleep efficiency,sleep disorders,hypnotic and day function and the total scores)in the western medicine group were less than those before treatment(P<0.01).The PQSI scores(sleep quality,time of falling asleep,sleep time,sleep efficiency,sleep disorders,hypnotic and day function)in the combined group were less than those in the traditional Chinese medicine group(P<0.01).The PQSI scores(sleep quality,time of falling asleep,sleep time,sleep efficiency,sleep disorders,hypnotic and day function)in the combined group were less than those in the traditional Chinese medicine group(P<0.05).After treatment,all dimensions of SF-36 in the traditional Chinese medicine group and the combined group were increased compared with those before treatment(P<0.01).The physical pain in the western medicine group was increased after treatment(P<0.01),the physical health,social function,physical role,mental health,emotional role,energy and overall health dimensions in the traditional Chinese medicine group and the combined

关 键 词：失眠 老年人 脑康Ⅱ号 中药穴位敷贴 睡眠质量 生活质量 

分 类 号：R47[医药卫生—护理学]