冠脉支架内再狭窄发生率及其影响因素分析  

Analysis on Incidence of Coronary In-stent Restenosis and Its Influencing Factors

作　　者：简政威[1] 张晓明[1] JIAN Zhengwei;ZHANG Xiaoming(Dongguan People’s Hospital,Guangdong Province,Dongguan 523000,China;不详)

机构地区：[1]广东省东莞市人民医院,广东东莞523000

出　　处：《中国医学创新》2022年第18期114-117,共4页Medical Innovation of China

摘　　要：目的:探究及分析冠脉支架内再狭窄发生率及其影响因素。方法:方便抽样法选取2019年11月-2021年11月东莞市人民医院的300例冠脉支架患者为研究对象,将其冠脉支架内再狭窄发生率进行统计,比较不同个人基本情况(性别、年龄、体重指数、抽烟指数及饮酒情况)及疾病情况[糖尿病、高血压、高尿酸血症、低密度脂蛋白胆固醇(LDL-C)水平、甘油三酯(TG)水平、C反应蛋白(CRP)水平、病变部位、支架个数及支架直径]患者地再狭窄发生率,采用多因素logistic回归分析冠脉支架内再狭窄发生的影响因素。结果:300例冠脉支架患者中发生再狭窄29例,发生率为9.67%;不同性别、年龄、体重指数、饮酒情况、高血压情况、TG水平、病变部位及支架个数患者地再狭窄发生率比较,差异均无统计学意义(P>0.05),重度抽烟、糖尿病、高尿酸血症、高LDL-C水平、高CRP水平及支架直径<3.0 mm患者地再狭窄发生率均显著高于其他患者,差异均有统计学意义(P<0.05);多因素logistic回归分析显示,重度抽烟、糖尿病、高尿酸血症、高LDL-C水平、高CRP水平及支架直径<3.0 mm是冠脉支架内再狭窄发生的影响因素(P<0.05)。结论:冠脉支架内再狭窄发生率较高,且其发生的影响因素众多,可作为防控与干预措施制订的参考依据。Objective:To investigate and analyze the incidence of coronary in-stent restenosis and its influencing factors.Method:A total of 300 patients with coronary stent implantation in Dongguan People’s Hospital from November 2019 to November 2021 were selected for the study by convenient sampling,and the incidence of coronary in-stent restenosis of all the patients was counted,the incidence of restenosis in patients with different personnel basic information(gender,age,body mass index,smoking index and drinking situation)and disease information[diabetes,hypertension,hyperuricemia,low density lipoprotein cholesterol(LDL-C)level,triglyceride(TG)level,C reactive protein(CRP)level,lesion location,number of stents and diameter of stents]were compared,and the influencing factors of coronary in-stent restenosis were analyzed with multivariate logistic regression analysis.Result:A total of 29 cases of 300 patients with coronary stent were with restenosis,with an incidence of 9.67%;there were no significant differences in the incidence of restenosis among patients with different gender,age,body mass index,drinking situation,hypertension,TG level,lesion location and number of stents(P>0.05).The incidence of restenosis in patients with severe smoking,diabetes,hyperuricemia,high LDL-C level,high CRP level and stent diameter<3.0 mm were significantly higher than those in other patients,the differences were statistically significant(P<0.05);multivariate logistic regression analysis showed that severe smoking,diabetes,hyperuricemia,high LDL-C level,high CRP level and stent diameter<3.0 mm were the influencing factors of coronary in-stent restenosis(P<0.05).Conclusion:The incidence of in-stent restenosis is high,and there are many influencing factors,which can be used as a reference for the formulation of prevention,control and intervention measures.

关 键 词：冠脉支架 再狭窄 个人基本情况 疾病治疗措施 

分 类 号：R541.4[医药卫生—心血管疾病]