补肺益肾平喘汤联合沙美特罗替卡松治疗慢性阻塞性肺疾病稳定期临床研究  

Clinical Study on Bufei Yishen Pingchuan Tang Combined with Salmeterol Rotticasone for Chronic Obstructive Pulmonary Disease at Stable Stage

作　　者：苏杭 王俊升 郑敏超 SU Hang;WANG Junsheng;ZHENG Minchao

机构地区：[1]台州市路桥区第二人民医院内科,浙江台州318058

出　　处：《新中医》2022年第11期92-95,共4页New Chinese Medicine

摘　　要：目的:观察补肺益肾平喘汤联合沙美特罗替卡松治疗慢性阻塞性肺疾病(COPD)稳定期的临床疗效。方法:选取COPD稳定期患者78例,按随机数字表法分为对照组和观察组各39例。对照组予沙美特罗替卡松吸入治疗,观察组在对照组基础上加补肺益肾平喘汤治疗,2组均连用12周。比较2组临床疗效,检测治疗前后肺功能指标第1秒用力呼气容积(FEV_(1))、用力肺活量(FVC)及FEV_(1)/FVC比值,比较2组呼吸困难量表(mMRC)评分和慢性阻塞性肺病评估量表(CAT)评分变化。结果:观察组总有效率为94.87%,高于对照组79.49%,差异有统计学意义(P<0.05)。治疗前,2组FEV_(1)、FVC及FEV_(1)/FVC比较,差异无统计学意义(P>0.05)。治疗后,2组FEV_(1)、FVC及FEV_(1)/FVC较治疗前升高,且观察组FEV_(1)、FVC及FEV_(1)/FVC高于对照组,差异有统计学意义(P<0.05)。治疗前,2组mMRC评分、CAT评分比较,差异无统计学意义(P>0.05)。治疗后,2组mMRC评分、CAT评分较治疗前下降(P<0.05),且观察组mMRC评分、CAT评分低于对照组(P<0.05)。结论:补肺益肾平喘汤联合沙美特罗替卡松治疗COPD稳定期患者的疗效确切,能明显改善临床症状及肺功能。Objective:To observe the clinical effect of Bufei Yishen Pingchuan tang combined with salmeterol rotticasone for chronic obstructive pulmonary disease(COPD)at stable stage.Methods:A total of 78 cases of COPD patients at stable stage were selected and divided into the control group and the observation group,with 39 cases in each group.The control group was given salmeterol rotticasone inhalation,and the observation group was additionally treated with Bufei Yishen Pingchuan tang based on the treatment of the control group.Both groups were treated for 12 weeks.Clinical effects were compared between the two groups.The lung function indexes including forced expiratory volume in one second(FEV_(1)),forced vital capacity(FVC),and the ratio of FEV_(1)to FVC before and after treatment were detected.Changes in scores of Modified Medical Research Council(mMRC)and COPD Assessment Test(CAT)were compared between the two groups.Results:The total effective rate was 94.87%in the observation group,higher than that of 79.49%in the control group,the difference being significant(P<0.05).Before treatment,there was no significant difference being found in the comparison of FEV_(1),FVC and FEV_(1)/FVC between the two groups(P>0.05).After treatment,FEV_(1),FVC and FEV_(1)/FVC in the two groups were increased when compared with those before treatment,and the three indexes in the observation group were higher than those in the control group,the difference being significant(P<0.05).Before treatment,there was no significant difference being found in the comparison of scores of mMRC and CAT between the two groups(P>0.05).After treatment,scores of mMRC and CAT in the two groups were decreased when compared with those before treatment,and the scores of mMRC and CAT in the observation group were lower than those in the control group(P<0.05).Conclusion:Bufei Yishen Pingchuan tang combined with salmeterol rotticasone has a defined curative effect in the treatment of COPD patients at stable stage,and it can more effectively improve clinical symptom

关 键 词：慢性阻塞性肺疾病 稳定期 补肺益肾平喘汤 沙美特罗替卡松 肺功能 呼吸困难量表 慢性阻塞性肺病评估量表 

分 类 号：R563[医药卫生—呼吸系统]