糖尿病下肢动脉硬化闭塞症中医证型与股总动脉内膜中层厚度的关系  

Relationship between traditional Chinese medicine syndrome type of diabetes lower extremity arteriosclerosis obliterans and intima-media thickness of common femoral artery

作　　者：鞠燕玲 王彬[2] Ju Yanling;Wang Bin(First Clinical Medical College,Shandong University of Traditional Chinese Medicine,Ji'nan 250014,Shandong,China;Department of Peripheral Vascular Disease,Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Ji'nan 250014,Shandong,China)

机构地区：[1]山东中医药大学第一临床医学院,山东济南250014 [2]山东中医药大学附属医院周围血管病科,山东济南250014

出　　处：《血管与腔内血管外科杂志》2022年第4期439-442,共4页Journal of Vascular and Endovascular Surgery

基　　金：山东省中医药科技发展计划项目(2019-0664)。

摘　　要：目的分析糖尿病下肢动脉硬化闭塞症(DLASO)患者中医证型与股总动脉内膜中层厚度(CFA-IMT)的关系。方法收集2020年1月至2021年8月山东中医药大学附属医院收治的80例DLASO患者的临床资料,根据不同的中医证型将其分为湿热证组及血瘀证组,各40例。记录两组患者的性别、年龄、糖化血红蛋白(HbA1c)、总胆固醇(TC)、低密度脂蛋白(LDL)、中性粒细胞-淋巴细胞比(NLR)及CFA-IMT,并分析两组患者与上述指标之间的关系。结果湿热证组患者CFA-IMT增厚程度高于血瘀证组患者,湿热证组患者年龄小于血瘀证组患者,差异均有统计学意义(P<0.05)。两组患者性别、NLR、HbA1c、TC、LDL比较,差异均无统计意义(P>0.05)。结论CFA-IMT值及年龄可预测DLASO的中医证型,且简便易行,可以考虑将其作为DLASO中医证型的客观化理论依据。Objective To analyze the relationship between traditional Chinese medicine(TCM)syndrome type and common femoral artery intima-media thickness(CFA-IMT)in patients with diabetes lower extremity arteriosclerosis obliterans(DLASO).Method The clinical data of 80 DLASO patients admitted to Affiliated Hospital of Shandong University of Traditional Chinese Medicine from January 2020 to August 2021 were collected,all subjects were divided into damp-heat syndrome group and blood-stasis syndrome group according to different TCM syndrome types,with 40 cases in each group.The gender,age,glycosylated hemoglobin(HbA1c),total cholesterol(TC),low-density lipoprotein(LDL),neutrophil-lymphocyte ratio(NLR)and CFA-IMT of the two groups of patients were recorded.The relationship between the two groups of patients and the above indicators was analyzed.Result The grade of CFA-IMT thickening in the dampheat syndrome group was higher than that in the blood-stasis syndrome group,the age of the damp-heat syndrome group was smaller than that of the blood-stasis syndrome group,the differences were statistically significant(P<0.05).There were no significant differences in gender,NLR,HbA1c,TC,and LDL between the two groups(P>0.05).Conclusion The CFA-IMT value and age could predict the TCM syndrome types of DLASO,it is simple and easy to implement.The value can be considered as an objective theoretical basis for the TCM syndrome types of DLASO.

关 键 词：糖尿病下肢动脉硬化闭塞症 中医证型 中性粒细胞-淋巴细胞比 股动脉内膜中层厚度 

分 类 号：R543[医药卫生—心血管疾病]