芩蒌清利汤结合火针治疗湿疹(湿热证)临床疗效观察  

Clinical Effect Observation of Qinlou Qingli Decoction(芩蒌清利汤)Combined with Fire Acupuncture in Treatment of Eczema(Damp-Heat Syndrome)

作　　者：涂焱华 时文远 袁朵 TU Yanhua;SHI Wenyuan;YUAN Duo(Shiyan People's Hospital,Affiliated People's Hospital of Hubei College of Medicine,Shiyan 442099,Hubei,China;Shenzhen Longhua District Maternal and Child Health Hospital,Shenzhen 518040,Guangdong,China)

机构地区：[1]十堰市人民医院,湖北医药学院附属人民医院,湖北十堰442099 [2]深圳市龙华区妇幼保健院,广东深圳518040

出　　处：《中华中医药学刊》2022年第4期191-194,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：湖北省卫建委中医药科研立项项目(ZY2021M003)。

摘　　要：目的探究芩蒌清利汤结合火针治疗湿疹(湿热证)临床疗效及安全性。方法研究共计纳入湿疹(湿热证)患者68例,均由医院中医科2018年1月—2021年1月收治,并采取随机数字表法将纳入的68例患者平均分成两组,对照组患者采取西医常规治疗方法,观察组患者采取西医常规治疗方法+芩蒌清利汤结合火针治疗,比较两组患者治疗效果、治疗前后患者中医证候(皮损、瘙痒无休、身热心烦、口渴便干、尿短赤等)积分变化、患者治疗后起效时间、治疗前后患者湿疹严重程度指数(EASI)评分变化及瘙痒严重程度评分变化(视觉模拟疼痛评分法,VAS)、皮损评分变化、治疗前后患者血清炎症因子水平变化、不良反应情况。结果观察组与对照组有效率比较,观察组更高,P<0.05;观察组患者治疗起效时间优于对照组(P<0.05);治疗前,两组患者中医证候(皮损、瘙痒无休、身热心烦、口渴便干、尿短赤等)积分、EASI评分及VAS评分、皮损评分、血清炎症因子白介素-2(IL-2)及白介素-4(IL-4)水平等指标比较,P>0.05,治疗后各组患者中医证候(皮损、瘙痒无休、身热心烦、口渴便干、尿短赤等)积分、EASI评分及VAS评分、皮损评分、血清炎症因子IL-2及IL-4水平等指标改善,观察组患者治疗后中医证候(皮损、瘙痒无休、身热心烦、口渴便干、尿短赤等)积分、EASI评分及VAS评分、皮损评分、血清炎症因子IL-2及IL-4水平等指标均优于对照组(P<0.05);两组不良反应率均较低,观察组为5.88%(2/34),对照组为2.94%(7/34),P>0.05。结论芩蒌清利汤结合火针治疗湿疹(湿热证)临床疗效显著,患者瘙痒、皮损等症状改善,恢复较好、恢复快,不良反应少,安全可行,值得应用及推广。Objective To explore the clinical efficacy and safety of Qinlou Qingli Decoction(芩蒌清利汤)combined with fire acupuncture in the treatment of eczema(damp-heat syndrome).Methods A total of 68 cases of eczema(damp-heat syndrome)in the hospital from January 2018 to January 2021 were analyzed,and according to the random number table method,the patients were divided into two groups on average.The control group's patients were treated with western medicine routine treatment.The observation group's patients were treated with western medicine routine treatment and Qinlou Qingli Decoction combined with fire needle therapy.Before and after treatment,TCM syndromes integral(skin lesions,itching,hot and upset,thirsty and dry,short and red urine,etc),the prominent effect time,severity index score(EASI)and itching severity score changes(VAS),changes in skin lesions,changes in serum inflammatory factors before and after treatment and adverse reactions of two groups were compared.Results The effective rate of the observation group was higher than that of the control group(P<0.05).The onset time of treatment in the observation group was better than that of the control group(P<0.05).Before treatment,the scores of TCM syndrome,EASI score,VAS score,skin lesion score,serum levels of inflammatory cytokines interleukin-2(IL-2)and interleukin-4(IL-4)between two groups had no significance(P>0.05).After treatment,TCM syndrome scores,EASI score,VAS score,skin lesion score,serum inflammatory cytokines IL-2 and IL-4 levels were improved in each group.After treatment,the TCM syndrome score,EASI score,VAS score,skin lesion score,serum inflammatory cytokines IL-2 and IL-4 levels in the observation group were better than those in the control group(P<0.05).The adverse reaction rate of the two groups was low.The adverse reaction rate of the observation group was 5.88%(2/34)and that of the control group was 2.94%(1/34)(P>0.05).Conclusion The clinical effect of Qinlou Qingli Decoction combined with fire acupuncture in the treatment of eczema(da

关 键 词：湿疹 湿热证 芩蒌清利汤 火针 疗效 湿疹严重程度指数 瘙痒严重程度 皮损 

分 类 号：R245.36[医药卫生—针灸推拿学] R275.958.23[医药卫生—中医临床基础]