不稳定性心绞痛痰瘀互结证病理机制与临床证治  

Analysis of Pathological Mechanism and Clinical Treatment of Unstable Angina Pectoris with Phlegm and Blood Stasis Syndrome

作　　者：高毛毛 杨硕[2] 汪阳 张秋英[2] GAO Maomao;YANG Shuo;WANG Yang;ZHANG Qiuying(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China;The Fourth Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110101,Liaoning,China)

机构地区：[1]辽宁中医药大学,辽宁沈阳110847 [2]辽宁中医药大学附属第四医院,辽宁沈阳110101

出　　处：《实用中医内科杂志》2022年第4期57-60,共4页Journal of Practical Traditional Chinese Internal Medicine

基　　金：辽宁省教育厅项目(L201727)。

摘　　要：痰瘀互结证型的提出源自《黄帝内经》中关于津血同病的研究。古代、现代中医各家对痰瘀互结证的研究众多,在疾病的发生和发展过程中痰、瘀两者彼此既是相互独立的证候要素和病理产物,又是疾病在病证转变和病情转归过程中的重要病理因素,尤其在心病的诊治过程中,往往痰瘀互结贯穿疾病的全程。从痰瘀互结病机证候理论着手探析不稳定心绞痛的治疗,从古籍文献源流发现,痰瘀互结为胸痹的关键致病因素,现今更多研究重视胸痹痰瘀互结证之辨证论治。不稳定心绞痛痰瘀互结证与西医学的“炎症因子”“氧化应激”“微循环障碍”等病理机制关系密切。临证应基于痰瘀互结辨证治疗不稳定性心绞痛,灵活应用祛痰、活血中药对不稳定性心绞痛进行治疗,为临床应用提供依据。The phlegm and blood stasis syndrome was proposed from the research on the same disease of body fluid and blood in Yellow Emperor’s Classic of Internal Medicine.There are many studies on the mutual formation of phlegm and blood stasis in ancient and modern traditional Chinese medicine.The important pathological factors in the process of prognosis,especially in the process of diagnosis and treatment of heart disease,often stagnate phlegm and blood stasis throughout the whole course of the disease.This study started from the pathogenesis and syndrome theory of phlegm and blood stasis and analyzed the treatment of unstable angina pectoris.From the source of ancient books and documents,it is found that phlegm and blood stasis are the key pathogenic factors of chest pain.Nowadays,more researches pay attention to chest pain and phlegm and blood stasis.Unstable angina pectoris is closely related to the pathological mechanisms of"inflammatory factors","oxidative stress"and"microcirculation disturbance"in western medicine.Clinical syndromes should be based on syndrome differentiation of phlegm and blood stasis to treat unstable angina pectoris,and flexible use of phlegm-resolving and blood-activating traditional Chinese medicines should be used to treat unstable angina pectoris,so as to provide a basis for clinical application.

关 键 词：冠心病 急性冠脉综合征 不稳定心绞痛 中医药 痰瘀互结 

分 类 号：R259[医药卫生—中西医结合]