前列腺动脉介入栓塞术治疗前列腺体积超过80毫升良性前列腺增生患者的疗效  

Efficacy of prostatic arterial interventional embolization in the treatment of benign prostatic hyperplasia patients with prostatic volume greater than 80 milliliter

作　　者：管玉婷 廖立安[1] 张展尚 陈建平[1] 罗明 黄丽[1] 曾国斌[1] Guan Yuting;Liao Li′an;Zhang Zhanshang;Chen Jianping;Luo Ming;Huang Li;Zeng Guobin(Department of Intervention,Meizhou People′s Hospital,Meizhou 514031,China)

机构地区：[1]梅州市人民医院介入科,梅州514031

出　　处：《中国医师进修杂志》2022年第6期526-530,共5页Chinese Journal of Postgraduates of Medicine

基　　金：梅州市科技计划项目(2019B024)。

摘　　要：目的探讨前列腺动脉介入栓塞术治疗前列腺体积>80 ml良性前列腺增生(BPH)患者的疗效。方法选取2018年4月至2020年11月梅州市人民医院诊治的合并高血压、糖尿病、心脏病等基础疾病的前列腺体积>80 ml的BPH患者58例,按随机数字表法分为研究组与对照组,每组28例。研究组采取前列腺动脉介入栓塞术,对照组采取经尿道前列腺切除术。比较两组的疗效和围手术期情况及术前、术后1个月血清总前列腺特异抗原(TPSA)、游离前列腺特异抗原(FPSA)、前列腺体积、国际前列腺症状评分(IPSS),比较两组术后6个月性生活质量的差异。结果两组总有效率比较差异无统计学意义(P>0.05)。研究组术中失血量、尿管留置时间、住院时间均少于对照组[(10.65±1.89)ml比(119.64±23.60)ml、(2.16±0.39)d比(3.05±0.61)d、(3.03±1.82)d比(7.10±2.39)d],差异有统计学意义(P<0.05)。两组术后1个月血清TPSA和FPSA水平、前列腺体积、IPSS比较差异均无统计学意义(P>0.05)。研究组术后6个月早泄患者性功能评定量表-5、国际勃起功能评定量表评分高于对照组[(18.63±2.51)分比(15.71±2.29)分、(16.38±4.14)分比(13.98±3.82)分],差异均有统计学意义(P<0.05)。结论前列腺动脉介入栓塞术在前列腺体积>80 ml BPH合并基础疾病患者中的应用效果显著,与经尿道前列腺切除术比较,具有术后恢复快的优势,在控制疾病、改善排尿功能、提高性生活质量方面效果理想。Objective To investigate the effect of interventional embolization of prostate artery in patients with benign prostatic hyperplasia with prostatic volume>80 ml.Methods A total of 56 patients with BPH combined with hypertension,diabetesand heart disease with prostate volume>80 ml in Meizhou People′s Hospital from April 2018 to November 2020 were selected.They were divided into the study group and the control group according to a simple random number table,28 cases in each group.The patients in the study group were performed prostatic arterial embolization,and the patients in the control group were performed transurethral resection of the prostate.The efficacy,perioperative conditions,preoperative and 1 month after operation serum total prostate specific antigen(TPSA)level,free prostate specific antigen(FPSA)level,prostate volume,and international prostate symptom score(IPSS)were compared between the two groups.The sexual life quality after operation for 6 months was compared between the two groups.Results The efficacy of the two groups had no significant difference(P>0.05).The intraoperative blood loss,postoperative catheterization,postoperative hospital stay in the study group were less than those in the control group:(10.65±1.89)ml vs.(119.64±23.60)ml,(2.16±0.39)d vs.(3.05±0.61)d,(3.03±1.82)d vs.(7.10±2.39)d,the differences were statistically significant(P<0.05).The levels of serum TPSA,FPSA and prostate volume,IPSS at the first month after surgery in the two groups had no significant differences(P>0.05).After operation for 6 months,the scores of Chinese Index of Sexual Function for Premature Ejaculation-5(CIPE-5)and International Index of Erectile Function(IIEF-5)in the study group were higher than those in the control group:(18.63±2.51)scores vs.(15.71±2.29)scores,(16.38±4.14)scores vs.(13.98±3.82)scores,the differences were statistically significant(P<0.05).Conclusions Prostate arterial embolization is effective in BPH patients with prostate volume>80 ml and underlying diseases.Compared with trans

关 键 词：栓塞 治疗性 前列腺增生 经尿道前列腺切除术 治疗结果 疗效比较 

分 类 号：R699.8[医药卫生—泌尿科学]