某院210例细菌性肠炎患儿大便标本中病原菌的分布与耐药性分析  

Analysis of Distribution and Drug Resistance of Pathogenic Bacteria in Stool Specimens of 210 Children with Bacterial Enteritis in a Hospital

作　　者：李朝卫 LI Chao-wei(Department of Pediatrics,Luoyang New District People's Hospital,Luoyang Henan 471027,China)

机构地区：[1]洛阳新区人民医院儿科,河南洛阳471027

出　　处：《抗感染药学》2022年第3期335-337,共3页Anti-infection Pharmacy

摘　　要：目的:分析医院细菌性肠炎患儿大便标本中病原菌的分布与耐药特点。方法:选取2019年2月—2021年2月洛阳新区人民医院收治的210例细菌性肠炎患儿的病历资料,分析患儿大便标本中病原菌的分布与耐药情况。结果:210例细菌性肠炎患儿大便标本中共分离出病原菌240株,其中革兰阴性菌185株(占77.08%,主要为大肠埃希菌、福氏志贺菌、沙门菌属)和革兰阳性菌55株(占22.92%,主要为粪肠球菌、金黄色葡萄球菌);药敏结果显示,大肠埃希菌、福氏志贺菌、沙门菌属等主要革兰阴性菌对美罗培南、亚胺培南的耐药率均为0.00%;粪肠球菌和金黄色葡萄球菌对万古霉素的耐药率均为0.00%。结论:细菌性肠炎患儿的病原菌主要为革兰阴性菌,临床应根据微生物培养和药敏试验结果合理选用抗菌药物治疗。Objective:To analyze distribution and drug resistance characteristics of pathogenic bacteria in stool specimens of children with bacterial enteritis in the hospital.Methods:The medical records of 210 children with bacterial enteritis admitted to Luoyang New District People's Hospital from February 2019 to February 2021 were selected to analyze the distribution and drug resistance of pathogenic bacteria in stool specimens of the children.Results:A total of 240 pathogenic bacteria were isolated from the stool specimens of 210 children with bacterial enteritis,including 185 Gram-negative bacteria(77.08%,mainly Escherichia coli,Shigella flexneri and Salmonella)and 55 Gram-positive bacteria(22.92%,mainly Enterococcus faecalis and Staphylococcus aureus);the drug susceptibility results showed that the drug resistance rates of major Gram-negative bacteria such as Escherichia coli,Shigella flexneri and Salmonella to meropenem and imipenem were 0.00%;the drug resistance rates of Enterococcus faecalis and Staphylococcus aureus to vancomycin were 0.00%.Conclusion:The pathogenic bacteria in children with bacterial enteritis are mainly Gramnegative bacteria,and antibacterial drugs should be reasonably selected for treatment in clinic practices according to the results of microbial culture and drug susceptibility tests.

关 键 词：细菌性肠炎 病原菌 耐药性 

分 类 号：R915[医药卫生—微生物与生化药学] R969.3[医药卫生—药学]