2-羟丙基-β-环糊精对槲皮素的包合作用  

Encapsulation of quercetin with 2-hydroxypropyl-β-cyclodextrin

作　　者：吴雨婷 钱永芳 吕丽华 王迎 WU Yuting;QIAN Yongfang;LYU Lihua;WANG Ying(School of Textile and Material Engineering,Dalian Polytechnic University,Dalian 116034,Liaoning,China)

机构地区：[1]大连工业大学纺织与材料工程学院,辽宁大连116034

出　　处：《上海纺织科技》2022年第4期61-64,共4页Shanghai Textile Science & Technology

基　　金：2019年大连市科技创新基金项目(2019J12SN71)。

摘　　要：通过旋转蒸发法制备了槲皮素/2-羟丙基-β-环糊精包合物(Qu/2-HP-β-CD-IC),并采用静电纺丝法将其负载到纳米纤维膜上。通过扫描电镜(SEM)、红外光谱(FTIR)、差示扫描量热分析(DSC)、X射线衍射(XRD)等方法对包合物进行表征。结果表明:在Qu与2-HP-β-CD的摩尔比为1∶1,包合温度为60℃,包合时间为2 h的条件下,成功制备了槲皮素/2-羟丙基-β-环糊精包合物;在相同温湿度条件下,负载槲皮素/2-羟丙基-β-环糊精包合物的纤维膜的抗紫外线性能更佳,槲皮素的生物利用度得到提高。Quercetin/2-hydroxypropyl-β-cyclodextrin inclusion complex(Qu/2-HP-β-CD-IC)is prepared by rotary evaporation and loaded into nanofiber membranes by electrostatic spinning.The inclusion compounds are characterized by scanning electron microscopy(SEM),infrared spectra analysis(FTIR),differential scanning calorimetry(DSC)and X-ray diffraction(XRD).The results show that the quercetin/2-hydroxypropyl-β-cyclodextrin inclusion complex is successfully prepared when the molar ratio of host to guest is 1∶1,the inclusion temperature is 60℃and the inclusion time is 2 h.Under the same temperature and humidity conditions,the fiber membrane loaded with quercetin/2-hydroxypropyl-β-cyclodextrin inclusion compound has better UV resistance,and the bioavailability of quercetin is im⁃proved.

关 键 词：静电纺 纳米纤维 抗紫外 槲皮素 2-羟丙基-Β-环糊精 包合物 

分 类 号：TS102.54[轻工技术与工程—纺织工程]