强化营养治疗对慢性阻塞性肺疾病认知功能的效果观察  

Effect of Enhanced Nutrition on Cognitive Function of Chronic Obstructive Pulmonary Disease

作　　者：王晓静[1] 肖凤仙[2] 吕春萍 杨卫 Wang Xiaojing;Xiao Fengxian;Lv Chunping;Yang Wei(Department of General Medicine,Baoding First Central Hospital,Baoding 071000,Hebei Province,China;不详)

机构地区：[1]保定市第一中心医院,河北省保定市071000 [2]保定市第二中心医院临床营养科,河北省保定市涿州市072750 [3]解放军第82集团军医院营养科,河北省保定市071000

出　　处：《中国病案》2022年第6期97-100,共4页Chinese Medical Record

摘　　要：目的 探讨强化磷脂酰丝氨酸(PS)肠内营养治疗对老年慢性阻塞性肺疾病(COPD)急性加重期患者认知功能的影响。方法 将2018年4月1日-2019年10月1日期间某院收治的老年慢阻肺急性加重期患者64例作为本次研究对象,依据随机数字表法,将其分为对照组32例与研究组32例。对照组单纯给予肠内营养治疗,研究组给予"肠内营养+磷脂酰丝氨酸200mg/天"。分析比较两组营养指标、微型营养评价量表(MNA)评分、降钙素原(PCT)水平及MMSE评分。结果 治疗后两组血清白蛋白水平与血清前白蛋白水平、MNA评分、MMSE评分均高于治疗前(P<0.05),且治疗后研究组血清白蛋白水平与血清前白蛋白水平、MNA评分、MMSE评分均高于对照组(P<0.05)。治疗后两组PCT水平均低于治疗前(P<0.05),且治疗后研究组PCT水平低于对照组(P<0.05)。结论 强化磷脂酰丝氨酸(PS)肠内营养治疗可明显改善老年慢阻肺急性加重期患者的认知功能。Objectives To investigate the effects of enhanced phosphatidylserine(PS) enteral nutrition on cognitive function in elderly patients with acute exacerbation of chronic obstructive pulmonary disease(COPD).Methods 64 elderly patients with acute exacerbation of COPD in a hospital from April 1st,2018 to October 1st,2019were selected as the subjects of this study.According to the random number table method,they were divided into control group(n = 32) and study group(n = 32).The control group was given enteral nutrition alone,and the study group was given enteral nutrition combined with phosphatidylserine 200mg/day.Nutritional indexes,MNA score,procalcitonin(PCT) level and MMSE score of the two groups were analyzed and compared.Results After treatment,the serum albumin level,prealbumin level,MNA score and MMSE score of the two groups were higher than those before treatment(P<0.05),and the serum albumin level,prealbumin level,MNA score and MMSE score of the study group were higher than those of the control group(P<0.05).After treatment,the level of PCT in both groups was lower than before(P<0.05),and the level of PCT in the study group was lower than that in the control group(P<0.05).Conclusions Enhanced phosphatidylserine(PS) enteral nutrition could significantly improve the cognitive function of elderly patients with acute exacerbation of COPD.

关 键 词：磷脂酰丝氨酸 慢阻肺急性加重期 肠内营养 微型营养评价量表 降钙素原 简易智力状态检查量表 

分 类 号：R563.9[医药卫生—呼吸系统]