Meta流行病学的产生与发展  

Meta-epidemiology: origin and development

作　　者：龙囿霖 林春滢 郭嘉琪 王心怡 杨柳[2] 程祎凡 黄进[1,2] 杨克虎[4,5,6] 章仲恒 徐畅[8] 商洪才 杜亮[1,2] LONG Youlin;LIN Chunying;GUO Jiaqi;WANG Xinyi;YANG Liu;CHENG Yifan;HUANG Jin;YANG Kehu;ZHANG Zhongheng;XU Chang;SHANG Hongcai;DU Liang(Medical Device Regulatory Research and Evaluation Center,West China Hospital,Sichuan University,Chengdu 610041,P.R.China;Chinese Evidence-based Medicine Center,West China Hospital,Sichuan University,Chengdu 610041,P.R.China;West China School of Public Health,Sichuan University,Chengdu 610041,P.R.China;Evidence-Based Medicine Center,School of Basic Medical Sciences,Lanzhou University,Lanzhou 730000,P.R.China;Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province,Lanzhou 730000,P.R.China;Evidence-Based Social Science Center,School of Public Health,Lanzhou University,Lanzhou 730000,P.R.China;Department of Emergency Medicine,Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,Hangzhou 310016,P.R.China;Department of Population Medicine,College of Medicine,Qatar University,Doha 2731,Qatar;Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,P.R.China)

机构地区：[1]四川大学华西医院医疗器械监管研究与评价中心,成都610041 [2]四川大学华西医院中国循证医学中心,成都610041 [3]四川大学华西公共卫生学院,成都610041 [4]兰州大学基础医学院循证医学中心,兰州730000 [5]甘肃省循证医学与临床转化重点实验室,兰州730000 [6]兰州大学公共卫生学院循证社会科学中心,兰州730000 [7]浙江大学医学院附属邵逸夫医院急诊医学科,杭州310016 [8]卡塔尔大学医学院人群医学系,多哈2731 [9]北京中医药大学东直门医院中医内科学教育部和北京市重点实验室,北京100700

出　　处：《中国循证医学杂志》2022年第6期716-721,共6页Chinese Journal of Evidence-based Medicine

基　　金：四川省科技厅项目(编号:2019YFS0194);国家自然科学基金项目(编号:81873197、72074161)。

摘　　要：当系统评价或临床试验受偏倚影响时可能会高估或低估干预的益处或危害,此时很可能得出错误结论。Meta流行病学研究是识别与量化潜在偏倚特征影响的重要工具,可为未来控制研究偏倚提供实证证据。本文介绍了Meta流行病学的产生背景、发展历程、定义,并讨论了当前存在的挑战及发展趋势,为未来开展Meta流行病学研究提供参考。Bias in clinical trials or systematic reviews may result in overestimation or underestimation of the benefits or harms of the interventions, and conclusions may be false. Meta-epidemiological study is an important tool to identify and quantify the impact of potential bias characteristics, and it can provide empirical evidence for controlling the bias. This paper summarized the origin, development and definition of the meta-epidemiology study, and discussed the challenges and development trends, so as to provide references for carrying out the meta-epidemiological studies.

关 键 词：Meta流行病学 定义 挑战 

分 类 号：R181[医药卫生—流行病学]