接种麻疹流行性腮腺炎风疹联合减毒活疫苗后发生麻疹2例病例报告  

Two cases of measles after vaccination with measles mumps and rubella combined live attenuated vaccine

作　　者：沈金花[1] 胡塔静[1] 陈文花[1] 钱婧娴 陆红梅[1] SHEN Jinhua;HU Tajing;CHEN Wenhua;QIAN Jingxian;LU Hongmei(Songjiang District Center for Disease Control and Prevention,Shanghai 201620,China)

机构地区：[1]上海市松江区疾病预防控制中心,上海201620

出　　处：《上海预防医学》2022年第5期446-447,468,共3页Shanghai Journal of Preventive Medicine

摘　　要：麻疹是由麻疹病毒引起的急性呼吸道传染病,该病传染性强,好发于儿童,容易引起气管炎、中耳炎、肺炎等多种严重并发症。自我国开始推广麻疹疫苗以来,麻疹疫情得到了有效控制。2020年6月1日起,上海市儿童的含麻疹成分疫苗免疫程序调整为8月龄、18月龄和6岁各接种1剂麻疹流行性腮腺炎风疹联合减毒活疫苗(MMR疫苗)。MMR疫苗注射后一般无局部反应,个别接种者可能出现一过性发热以及散在皮疹,一般可自行缓解。但由于其为减毒活疫苗,所以在极个别受种者可能会引起疫苗相关疾病,本文报道2例接种MMR疫苗后发生麻疹的病例。Measles is an acute respiratory infectious disease caused by the measles virus. It is highly infectious and easy to occur in children. It causes many serious complications such as tracheitis,otitis media and pneumonia. Since the promotion of the measles vaccine in China,the measles epidemic has been effectively controlled. From June 1,2020,the immunization procedure of measles-containing vaccine for children in Shanghai has been adjusted to one dose of measles,mumps and rubella combined live attenuated vaccine(MMR)at the age of 8 months,18months and 6 years. There is generally no local reaction after the injection of the MMR vaccine. A few individuals may have transient fever and scattered rash,which generally fade away by themselves. However,because it is a live vaccine,it may cause vaccine related diseases in extremely rare cases. This paper reports two cases of measles after vaccination with the MMR vaccine.

关 键 词：麻疹 麻疹流行性腮腺炎风疹联合减毒活疫苗(MMR疫苗) 麻疹IGM抗体 麻疹病毒标本核苷酸序列测定 疫苗株 

分 类 号：R511.1[医药卫生—内科学]