典型藏茵陈原植物(川西獐芽菜、椭圆叶花锚、湿生扁蕾)分子水平的研究进展  

Research Progress on Molecular Level of Typical Original Plants of Tibetan Wormwood(Swertia mussotii,Halenia elliptica D.and Gentianopsis paludosa)

作　　者：董志强 杜少波 陈晓文 谢惠春 DONG Zhiqiang;DU Shaobo;CHEN Xiaowen;XIE Huichun(Key Laboratory of Medicinal Plant and Animal Resources of Qinghai-Tibet Plateau in Qinghai Province,Qinghai Normal Unversity,Xining 810008,China)

机构地区：[1]青海师范大学生命科学学院,青海省青藏高原药用动植物资源重点实验室,青海西宁810008

出　　处：《安徽农学通报》2022年第11期13-15,28,共4页Anhui Agricultural Science Bulletin

基　　金：科技部“第二次青藏高原综合科学考察研究”生命地球化学循环与环境健康专题(2019QZKK0606);青海省重大科技专项青海生态环境价值评估及大生态产业发展综合研究(2019-SF-A12);青海省科技厅青海省青藏高原药用动植物资源重点实验室(2020-YJ�Y40);基于道地演变的5种多基源中藏药材品质评价及转录组研究(2017-ZJ-774);中国科学院2018年度“西部之光”人才培养引进项目(人字[2018]99号)。

摘　　要：藏茵陈是藏族药物历史悠久的八珍藏药之一,具有清热、解毒、清肝利胆的功效。藏茵陈分为獐牙菜属、花锚属、扁蕾属等,其中川西獐芽菜、椭圆叶花锚、湿生扁蕾分别为其属中最具有代表性的植物,药效佳,受到了越来越多的欢迎。近年来,药用植物在分子水平生物合成机制与调控、分子标记技术、次生代谢产物生物合成途径(基于转录组测序技术)等方面的研究已然成为现如今分子水平研究中最活跃、最热点的领域。该文通过查阅近年文献,从生物合成分子机制与调控、分子标记技术、次生代谢产物生物合成途径(基于转录组测序技术)等方面对3种典型藏茵陈植物(川西獐芽菜、椭圆叶花锚、湿生扁蕾)的研究进展进行了综述与展望,为其今后在分子水平上相关机制的研究提供参考。Tibetan Herba Artemisiae Scopariae is one of the eight Tibetan medicines with a long history of Tibetan medicine,which has the effects of clearing away heat,detoxifying,clearing away liver and benefiting gallbladder.Ti⁃betan Artemisia can be divided into Swertia,Anthurium and Flaveria,among which Swertia in western Swertia muss⁃otii,Halenia elliptica D.and Gentianopsis paludosa are the most representative plants with the best efficacy,which have gained more and more popularity.In recent years,the research on molecular mechanism and regulation of bio⁃synthesis in medicinal plants,molecular marker technology and biosynthetic pathway of secondary metabolites(based on transcriptome sequencing technology)have become the most active and hot fields in molecular level re⁃search.In this paper,the research progress of three typical Tibetan Artemisia plants(Swertia mussotii,Halenia ellip⁃tica D.and Gentianopsis paludosa)was summarized and prospected from three aspects,such as the research on mo⁃lecular mechanism and regulation of biosynthesis,molecular marker technology,and biosynthetic pathway of second⁃ary metabolites(based on transcriptome sequencing technology),so as to provide reference basis for the related mech⁃anism research at molecular level in the future.

关 键 词：獐牙菜 川西獐芽菜 椭圆叶花锚 湿生扁蕾 分子调控机制 

分 类 号：R282[医药卫生—中药学]