在对糖尿病酮症酸中毒昏迷患者治疗中胰岛素不同应用方式所发挥出的作用分析  

作　　者：郭俊杰 

机构地区：[1]庆阳市人民医院重症医学科,甘肃庆阳745000

出　　处：《人人健康》2022年第8期111-113,共3页Health for Everyone

摘　　要：目的:在糖尿病酮症酸中毒昏迷患者接受胰岛素、胰岛素泵持续皮下输注胰岛素治疗后,对其血糖指标变化、不良反应发生率、血糖达标所需时间、平均尿胴体转阴时间进行探寻。方法:实施对比性研究,病例为糖尿病酮症酸中毒昏迷,样本量66例,时间2019年12月至2020年12月。33例患者接受传统静脉滴注胰岛素医治,纳入静脉滴注组;另33例患者接受胰岛素泵持续皮下输注胰岛素治疗,纳入持续皮下输注组。对空腹血糖FBG、餐后2 h血糖PBG、糖化血红蛋白Hb A1c水平值、不良反应发生率和血糖达标所需时间、平均尿胴体转阴时间进行探寻。结果:治疗后,持续皮下输注组患者FBG(5.14±0.21)mmo L/L、2h PBG(8.19±0.32)mmo L/L、Hb A1(6.07±1.31)%,不良反应发生率3.03%;静脉滴注组患者FBG(7.14±1.17)mmo L/L、2h PBG(11.24±1.33)mmo L/L、Hb A1(8.32±1.44)%、并发症发生率21.21%。各项指标数据对比组间差异较大,统计学意义凸显(P<0.05);持续皮下输注组平均尿胴体转阴时间(4.19±0.15)h、平均尿胴体转阴时间(23.15±1.33)h,相比静脉滴注组的(7.89±1.33)h、(37.18±4.25)h而言均更短(P<0.05)。结论:糖尿病酮症酸中毒昏迷患者治疗中,应用胰岛素泵持续皮下输注胰岛素治疗方案的作用更佳,更有利于促使血糖早日达标,尿胴体早日转阴。Objective:To explore the traditional intravenous infusion of insulin,the insulin pump and the continuous subcutaneous infusion of insulin.Methods:A comparative study was conducted in diabetic ketoacidosis and coma,with a sample size of 66 patients,from December 2019 to December 2020.Thirty-three patients received traditional intravenous insulin infusion and summarized into the intravenous infusion group;another 33 patients received continuous subcutaneous insulin infusion with insulin pump into continuous skin Lower infusion group.Fasting blood glucose FBG,PBG,Hb A1c level value,incidence of adverse reactions and time required to achieve blood glucose standard,and average time of urinary carcass conversion were explored.Results:After treatment,FBG(5.14±0.21)mmo L/L,2h PBG(8.19±0.32)mmo L/L,Hb A1(6.07±1.31)%,ADR.3.03%;FBG(7.14±1.17)mmo L/L,2h PBG(11.24±1.33)mmo L/L,Hb A1(8.32±1.44)%,complication rate 21.21%.Statistical significance(p<0.05);mean time(4.19±0.15)h(23.15±1.33)h were shorter than(7.89±1.33)h and(37.18±4.25)h(p<0.05).Conclusion:Insulin is used in diabetic ketoacidosis The treatment plan of continuous pump subcutaneous insulin infusion is better,which is more conducive to the early standard of blood sugar and the early conversion of the urinary carcass.

关 键 词：糖尿病酮症酸中毒昏迷 传统静脉滴注胰岛素 胰岛素泵持续皮下输注 血糖 不良反应 

分 类 号：R58[医药卫生—内分泌]