检索规则说明:AND代表“并且”;OR代表“或者”;NOT代表“不包含”;(注意必须大写,运算符两边需空一格)
检 索 范 例 :范例一: (K=图书馆学 OR K=情报学) AND A=范并思 范例二:J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual
作 者:王旭 沈玉娟 曹建平 WANG Xu;SHEN Yu-juan;CAO Jian-ping(National Institute of Parasitic Diseases,Chinese Center for Disease Control and Prevention(Chinese Center for Tropical Diseases Research),NHC Key Laboratory of Parasite and Vector Biology,WHO Collaborating Center for Tropical Diseases,National Center for International Research on Tropical Diseases,Shanghai 200025,China)
机构地区:[1]中国疾病预防控制中心寄生虫病预防控制所(国家热带病研究中心),国家卫生健康委员会寄生虫病原与媒介生物学重点实验室,世界卫生组织热带病合作中心,国家级热带病国际联合研究中心,上海200025
出 处:《热带病与寄生虫学》2022年第3期136-148,共13页Journal of Tropical Diseases and Parasitology
基 金:国家自然科学基金项目(81772225);上海市公共卫生体系建设三年行动计划(2020—2022)重点学科项目(GWV-10.1-XK13);国家公益性卫生行业科研专项(201502021)。
摘 要:隐孢子虫(Cryptosporidium spp.)可通过人和动物进行传播进而引发人体隐孢子虫病,是导致全球腹泻最重要的六种病原体之一,对儿童和免疫功能低下人群威胁极大,并可引起突发公共卫生事件。隐孢子虫病目前尚无有效治疗和预防的药物和疫苗,防控难度极大,在世界范围内受到越来越多的关注和重视。为此,本文概述了自1987年我国报道第1例隐孢子虫病病例以来人体隐孢子虫感染情况,并对水源和食物污染、家养动物感染、季节性流行情况等传播风险因素进行了梳理,总结了我国隐孢子虫病的防控进展、面临的挑战以及防治策略等现实问题。现有的调查和研究结果显示,我国的人源性隐孢子虫分布广泛,HIV/AIDS患者、恶性肿瘤患者和吸毒人员等群体均是需要重点关注的易感人群,主要致病虫种包括人隐孢子虫(C.hominis)和微小隐孢子虫(C.parvum)。考虑到隐孢子虫病的风险因素和防控现状,我国应当在监测网络、防控措施、防治技术、水源净化和健康教育等方面实施综合防控策略,从“寄生虫-人类-保虫宿主-环境”等各个防治环节践行“One Health”理念,从而实现隐孢子虫病的有效监测和控制。Protozoa of Cryptosporidium spp.can be transmitted through humans and animals,causing human cryptospo-ridiosis,which was considered as one of the six most important pathogens of diarrhea in the world.It is a great threat to children and immunocompromised people,and may cause outbreak of public health events.However,there are no effec-tive drugs or vaccines for the treatment and prevention of this infection at present.Therefore,the prevention and control of cryptosporidiosis is extremely difficult,and has attracted more and more attention around the world.In this paper,we summarized the situation of cryptosporidium infection in human since the first case of cryptosporidiosis was reported in China in 1987,discussed the risk factors of Cryptosporidium spp.transmission such as water and food contamination,in-fection of domestic animals,and seasonal epidemic situation,and summarized the progress,challenges and strategies of cryptosporidiosis control in China.Based on the existing survey and research results,Cryptosporidium spp.that can in-fect humans are widely distributed in China,and patients of HIV/AIDS or malignant tumor and drug addicts are suscepti-ble population that call for attention.The main pathogenic species include C.hominis and C.parvum.Considering the risk factors and prevention and control status of cryptosporidiosis,comprehensive prevention and control strategies should be implemented in terms of monitoring networks,prevention and control measures,technologies,water purifica-tion and health education,and the"One Health"public health concept should be practiced in all links of"parasites-hu-mans-reservoir host-environment",so as to achieve effective monitoring and control of cryptosporidiosis in China.
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在链接到云南高校图书馆文献保障联盟下载...
云南高校图书馆联盟文献共享服务平台 版权所有©
您的IP:216.73.216.70