山楂鸡内金软糖对大、小鼠消化功能的影响  

The Influence of Charred Fructus Crataegi and Chicken Endothelium Corneum Gigeriae Galli Fondant on Digestive Function in Rats and Mice

作　　者：刘玮[1,2] 吴东 袁翊茗[2] 曾燕斌 LIU Wei;WU Dong;YUAN Yiming;ZENG Yanbin(Jiangxi University of Chinese Medicine,Nanchang 330006,China;China Resources Jiangzhong Pharmaceutical Group Co.,Ltd.,Nanchang 330006,China;National Pharmaceutical Engineering Center for Solid Preparation in Chinese Materia Medica,Nanchang 330006,China)

机构地区：[1]江西中医药大学,江西南昌330006 [2]华润江中制药集团有限公司,江西南昌330006 [3]中药固体制剂制造技术国家工程研究中心,江西南昌330006

出　　处：《现代食品》2022年第12期200-202,共3页Modern Food

摘　　要：目的:探究山楂鸡内金软糖对大、小鼠消化功能的影响。方法:实验期间,每天给大、小鼠灌胃0.83 g·kg^(-1)、1.67 g·kg^(-1)、5.00 g·kg^(-1)剂量的山楂鸡内金软糖1次,连续30 d,进行小鼠小肠运动实验、大鼠消化酶测定实验。结果:与对照组相比较,在小鼠小肠运动实验方面,高剂量组小鼠墨汁推进率高于模型对照组,差异有极显著意义(P<0.01),说明山楂鸡内金软糖对小鼠小肠运动有增强作用;在大鼠消化酶测定实验方面,3个剂量组大鼠胃蛋白酶活性单位、胃蛋白酶排出量均高于对照组,差异有极显著意义(P<0.01)。结论:山楂鸡内金软糖对大、小鼠消化功能具有促进作用。Objective:To explore the effect of charred fructus crataegi and chicken endothelium corneum gigeriae galli fondant on digestive function in rats and mice.Method:During the experiment,rats and mice were gavaged with 0.83 g·kg^(-1),1.67 g·kg^(-1) and 5.00 g·kg^(-1) charred fructus crataegi and chicken endothelium corneum gigeriae galli fondant once a day for 30 days.The small intestine movement test of mice and the digestive enzyme test of rats were carried out.Result:Compared with the control group,the ink propulsion rate of the high-dose group was significantly higher than that of the model control group in the small intestine movement experiment of mice(P<0.01),indicating that charred fructus crataegi and chicken endothelium corneum gigeriae galli fondant can enhance the small intestinal motility of mice;in the assay of rat digestive enzymes,the pepsin activity unit and pepsin excretion of rats in the three dose groups were higher.In the control group,the difference was extremely significant(P<0.01).Conclusion:Charred fructus crataegi and chicken endothelium corneum gigeriae galli fondant can promote the digestive function of rats and mice.

关 键 词：山楂鸡内金软糖 消化功能 大鼠 小鼠 

分 类 号：S661.5[农业科学—果树学]