诺如病毒感染的流行病学研究进展  

Progress in epidemiological research of norovirus infection

作　　者：王宇 高志勇[1] 贾蕾[1] 杨鹏[2] 王全意[1] 卢庆彬[3] 崔富强[3] Wang Yu;Gao Zhiyong;Jia Lei;Yang Peng;Wang Quanyi;Lu Qingbin;Cui Fuqiang(Institute for Infectious Disease and Endemic Disease Control,Beijing Center for Disease Prevention and Control,Beijing 100013,China;Office of Beijing Center for Global Health,Beijing Center for Disease Prevention and Control,Beijing 100013,China;Department of Laboratorial Science and Technology/Vaccine Research Center,School of Public Health,Peking University,Beijing 100191,China)

机构地区：[1]北京市疾病预防控制中心传染病地方病控制所,北京100013 [2]北京市疾病预防控制中心全球健康中心办公室,北京100013 [3]北京大学公共卫生学院卫生检验学系/疫苗评价中心,北京100191

出　　处：《中华流行病学杂志》2022年第6期974-980,共7页Chinese Journal of Epidemiology

基　　金：首都卫生发展科研专项(2020-2-1011)。

摘　　要：诺如病毒具有传染性强、传播途径多样、病原体易变异的特点,是人群急性胃肠炎散发发病和暴发疫情的主要病原体,对社会造成较大的疾病负担。本文对诺如病毒急性胃肠炎的疾病负担、诺如病毒变异及流行株、诺如病毒感染的防控、诺如病毒感染后免疫和疫苗研发的研究进展进行综述。With characteristics of high infectivity,diverse transmission routes and high variation,norovirus is the main pathogen of sporadic cases and outbreaks of acute gastroenteritis,resulting in a serious disease burden.This paper summarizes the latest progress in epidemiological research of norovirus infection from aspects of disease burden caused by acute gastroenteritis,virus variation and predominant strains,prevention and control measures,and immunization and vaccine development.

关 键 词：诺如病毒 疾病负担 预防控制 疫苗 

分 类 号：R512.5[医药卫生—内科学] R181.3[医药卫生—临床医学]