运动干预对化疗期急性白血病患儿癌因性疲乏的影响  

Effect of exercise intervention on cancer-related fatigue in children with acute leukemia during chemotherapy

作　　者：沈晓雯 周红花 郑小芬 欧云霞 张惠惠 王闰平[2] 叶慧雯 邹萍 张春梅[4] Shen Xiaowen;Zhou Honghua;Zheng Xiaofen;Ou Yunxia;Zhang Huihui;Wang Runping;Ye Huiwen;Zou Ping;Zhang Chunmei(The Second Affiliated Hospital of Wenzhou Medical University,Wenzhou 325035,China)

机构地区：[1]温州医科大学第二临床医学院,浙江温州325000 [2]温州医科大学附属第二医院/育英儿童医院儿童血液病区 [3]School of Nursing,Nipissing University [4]温州医科大学附属第二医院/育英儿童医院党政综合办公室

出　　处：《护理学杂志》2022年第12期72-74,共3页Journal of Nursing Science

基　　金：浙江省自然基金基础公益类项目(LGF21G0LGF21G020002);温州市重大科技创新攻关项目(ZY2020022)。

摘　　要：目的探讨运动干预对化疗期急性白血病患儿癌因性疲乏及生活质量的改善效果。方法将60例急性白血病患儿按照住院时间段分为两组各30例。对照组接受常规护理;观察组在常规护理基础上实施运动干预,包括运动前评估、根据不同运动负荷进行运动及运动监测。采用多维疲乏量表、儿童普适性生活质量量表评价效果。结果干预12周后,干预组疲乏总分、生活质量总分显著高于对照组(均P<0.05)。结论运动干预可有效改善化疗期急性白血病患儿癌因性疲乏,提高患儿生活质量。Objective To explore the effect of exercise intervention on cancer-related fatigue and quality of life in children with acute leukemia during chemotherapy.Methods A total of 60 children with acute leukemia were divided into two groups according to either of the two periods they were hospitalized.The control group received routine nursing,while the intervention group was additionally subjected to an exercise intervention program(including pre-exercise assessment,exercise in pursuant to patients′exercise load,monitoring during exercise)during chemotherapy.The Multidimensional Fatigue Scale(MFS)and Pediatric Quality of Life Inventory 4.0(PedsQL4.0)were used to evaluate the effect.Results Twelves weeks into the intervention,the scores of fatigue and quality of life in the intervention group were significantly higher than those in the control group(P<0.05 for both).Conclusion Exercise intervention for children with acute leukemia during chemotherapy can effectively improve cancer-related fatigue and quality of life of children.

关 键 词：白血病 儿童 化疗 运动干预 癌因性疲乏 生活质量 

分 类 号：R473.72[医药卫生—护理学] R494[医药卫生—临床医学]