机构地区:[1]Department of Epidemiology,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100037,China [2]Key Laboratory of Cardiovascular Epidemiology,Chinese Academy of Medical Sciences,Beijing 100037,China [3]Department of Epidemiology and Biostatistics,College of Public Health,Zhengzhou University,Zhengzhou,Henan 450001,China [4]Department of Occupational and Environmental Health,School of Public Health,Tianjin Medical University,Tianjin 300070,China [5]Division of Epidemiology,Guangdong Provincial People's Hospital and Cardiovascular Institute,Guangzhou,Guangdong 510080,China [6]Department of Epidemiology,Center for Global Health,School of Public Health,Nanjing Medical University,Nanjing,Jiangsu 211166,China [7]Department of Cardiology,Fujian Provincial Hospital,Fuzhou,Fujian 350014,China [8]Cardio-Cerebrovascular Control and Research Center,Institute of Basic Medicine,Shandong Academy of Medical Sciences,Jinan,Shandong 250062,China [9]Center for Chronic and Noncommunicable Disease Control and Prevention,Sichuan Center for Disease Control and Prevention,Chengdu,Sichuan 610041,China [10]Department of Biostatistics and Epidemiology,School of Public Health,Shenzhen University Health Science Center,Shenzhen,Guangdong 518071,China [11]School of Medicine,Southern University of Science and Technology,Shenzhen,Guangdong 518055,China
出 处:《Chinese Medical Journal》2022年第6期747-749,共3页中华医学杂志(英文版)
基 金:supported by grants from the Chinese Academy of Medical Science Innovation Fund for Medical Sciences(Nos.2017-I2M-1-004,2019-I2M-2-003);the National Key Research and Development Program of China(Nos.2017YFC0211703,2018YFE0115300);the National Natural Science Foundation of China(No.91643208)。
摘 要:To the Editor:According to guidelines from western countries as well as China,dietary patterns with low intake of cholesterol have been widely recommended for maintaining ideal lipid levels.As one of the major sources of both high-quality protein and dietary cholesterol,eggs have always been the focus in terms of diet.Although increased lipid levels induced by high egg intake have been revealed by randomized controlled trials(RCTs),they may not be sufficient to reflect the impacts of habitual egg intake due to high doses of egg intake of more than 7 eggs/week or even 14 eggs/week.Further,RCTs typically have shorter intervention periods of about 3 months,which may not observe a stable association due to homeostasis in cholesterol metabolism of human beings.[1,2]Up to now,only three cohorts assessed the associations of egg intake with lipid levels or dyslipidemia,and the findings were still controversial.One recent cohort study has reported the non-significant association between higher egg intake(≥7 vs.1 eggs/week)and lipid profiles.On the other hand,another cohort from Spain found that compared with<1 egg/week,>4 eggs/week had no significant influence on total cholesterol(TC)and triglyceride(TG),but significantly decreased high-density lipoprotein cholesterol(HDL-C)levels.[4]However,none of these cohorts were from developing countries,and the association between moderate egg intake and lipid profiles has not been well illustrated.Egg consumption in China,a representative of developing countries,is relatively higher,and it may be possible to better explore the appropriate range of egg intake.
关 键 词:INTAKE METABOLISM doses
分 类 号:R195[医药卫生—卫生统计学]
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