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作 者:张国福 于先强 胡悦朋 杨琦 李维勤 Guo-Fu Zhang;Xian-Qiang Yu;Yue-Peng Hu;Qi Yang;Wei-Qin Li(Department of Critical Care Medicine,Affiliated Jinling Hospital,Medical School of Nanjing University,Nanjing 210002,Jiangsu Province,China;Medical College of Southeast University,Nanjing 210009,Jiangsu Province,China;Department of Critical Care Medicine,General Hospital of Eastern Theater Command,Nanjing 210002,Jiangsu Province,China)
机构地区:[1]南京大学医学院附属金陵医院(中国人民解放军东部战区总医院)重症医学科,江苏省南京市210002 [2]东南大学医学院,江苏省南京市210009
出 处:《世界华人消化杂志》2022年第12期541-546,共6页World Chinese Journal of Digestology
基 金:国家自然科学基金资助项目,No.81870441,82070669.
摘 要:妊娠期急性胰腺炎(acute pancreatitis in pregnancy,APIP)是妊娠期较少见却病情凶险的妊娠合并症,具有起病快、进展急、并发症多、病死率高等特点.据相关研究报道,APIP发病率约为1/10000-1/1000,且随胎龄的增加而升高.由于亚洲人群与欧美人群基因背景以及饮食生活习惯的差异,我国APIP的发病率高达1.14‰-2.27‰,显著高于西方国家.APIP的临床症状缺乏特异性,容易导致误诊或漏诊,极大增加了诊疗的难度.尽管对APIP的研究不断深入,然而其发病机制仍不明确.本文将对APIP的综合现状进行综述.Acute pancreatitis in pregnancy(APIP)is a rare and severe complication of pregnancy,which is characterized by rapid onset,rapid progression,many complications,and high mortality.According to previous studies,the incidence of APIP is about 1/10000-1/1000 and increases with gestational age.Due to the differences in genetic background and dietary habits between Asian and European populations,the incidence of APIP in China is as high as 1.14‰-2.27‰,significantly higher than that in Western countries.The lack of specific clinical symptoms of APIP often leads to misdiagnosis or missed diagnosis,which greatly increases the difficulty of diagnosis and treatment.Despite the deepening of the research on APIP,its pathogenesis is still unclear.This paper will give a systematical review of APIP.
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