CT技术用于肿瘤带电粒子治疗计划模拟研究  

Study of Oncology Charged Particle Therapy Planning Based on CT Technology

作　　者：张伟军[1] 彭红 ZHANG Wei-jun;PENG Hong(China Academy of Safety Science And Technology,Beijing 100029,China;Beijing Institute Occupation Disease Prevention and Treatment,Beijing 100093,China)

机构地区：[1]中国安全生产科学研究院,北京100029 [2]北京市职业病防治研究院,北京100093

出　　处：《核电子学与探测技术》2021年第6期919-924,共6页Nuclear Electronics & Detection Technology

基　　金：国家重点研发计划(2016YFC0801707)资助。

摘　　要：针对肿瘤带电粒子治疗计划系统入射能量之难以确定,本文通过模拟计算一定能量带电粒子在几种组织辐射等效材料中的射程与此能量带电粒子在水中射程的比值,用SRIM2008程序验证此比值可能为定值。研究CT值与此比值的函数关系;结合CT技术将带电粒子实际射程等效为水中的射程,反推入射带电粒子的能量。结果表明:在一定能量范围内,带电粒子在辐射等效材料中的射程与此能量带电粒子在水中的射程的比值恒定。CT值与此比值存在相关系数为R=0.999的函数关系。本结果可为CT技术用于肿瘤带电粒子治疗计划系统提供参考。In order to solve the problem of calculating the incident energy of charged particles in the treatment planning system of charged particles,this paper calculates the ratio of the range of charged particles with certain energy in several tissue radiation-equivalent materials to the range of charged particles in water by simulation.The SRIM 2008 program verifies that this ratio may be a constant value.The function relationship between CT value and this ratio is studied.Combined with CT technology,the actual range of charged particles is equivalent to the range of the water,and the energy of the charged particles is pushed back.The results show that the ratio of the range of charged particles in the radiationequivalent material to the range of the energy charged particles in the water is constant.There is a function relationship between the CT value and this ratio with a correlation coefficient of R=0.999.The results can be used as a reference for the application of CT in the treatment planning system of charged particles.

关 键 词：治疗计划系统 CT值 射程比值 水中等效射程 拟合函数 入射能量 

分 类 号：R811.1[医药卫生—放射医学]