急性甲醇中毒致视神经病变的临床特征及其随访转归  

Clinical features and follow-up outcomes of optic nerve injury induced by acute methanol poisoning

作　　者：吴娜[1] 宋玉果[1] Wu Na;Song Yuguo(Department of Occupational Medicine and Toxicology,Beijing Chaoyang Hospital,Capital Medical University,Beijing 100020,China)

机构地区：[1]首都医科大学附属北京朝阳医院职业病与中毒医学科,北京100020

出　　处：《中华劳动卫生职业病杂志》2022年第5期366-369,共4页Chinese Journal of Industrial Hygiene and Occupational Diseases

摘　　要：急性甲醇中毒危害视神经及中枢神经系统,可造成不可逆性损伤,严重者伴昏迷、甚至死亡。本文报道4例甲醇中毒患者。其中,3名患者误服含甲醇的工业酒精,较重的一名患者出现昏迷、视力下降等症状,毒物检测提示血甲醇浓度为869.3 μg/ml;1名患者为吸入性甲醇中毒,出现右眼全盲、左眼视力下降等症状。经过积极对症支持治疗,2例患者视力部分恢复,2例患者无后遗症。本文讨论了甲醇中毒致神经病变的临床特征和治疗预后,以提高对此病的认识。Acute methanol poisoning harms the optic nerve and central nervous system,can cause irreversible damage,even coma or death in severe cases.This article reported four cases of methanol poisoning.3 patients mistakenly ingested industrial alcohol containing methanol,the most serious patient suffered from coma,vision loss and other symptoms,the blood methanol concentration was 869.3μg/ml.Another patient was poisoning caused by inhalation of methanol,with symptoms such as total blindness in the right eye and decreased visual acuity in the left eye.After active supportive treatment,2 patients had partial recovery of visual acuity,and 2 patients had no sequelae.This article discussed the clinical features,treatment and prognosis of optic nerve damage caused by methanol poisoning,in order to raise awareness of this disease.

关 键 词：甲醇 中毒 血液透析 视神经 随访 

分 类 号：R595.6[医药卫生—内科学]