基于文献计量学的2016年至2021年全球乙型肝炎研究热点和趋势分析  

Global research hotspots and trends of hepatitis B from 2016 to 2021 based on analysis using bibliometric methods

作　　者：张琪然 侯雪林[2] 吴利俊 应峻[2] 张文宏[1] Zhang Qiran;Hou Xuelin;Wu Lijun;Ying Jun;Zhang Wenhong(National Medical Center for Infectious Diseases,Huashan Hospital,Fudan University,Shanghai 200040,China;Fudan University Library,Shanghai 200433,China)

机构地区：[1]国家传染病医学中心(复旦大学附属华山医院),上海200040 [2]复旦大学图书馆,上海200433

出　　处：《中华传染病杂志》2022年第3期129-136,共8页Chinese Journal of Infectious Diseases

基　　金：上海市加强公共卫生体系建设三年行动计划(2020—2022年)(GWV-3.1);上海市重点学科建设计划(GWV-10.1-XK01)。

摘　　要：目的对全球2016年至2021年乙型肝炎研究热点和趋势进行分析。方法检索2016年1月1日至2021年11月22日Web of Science核心合集数据库中收录的乙型肝炎相关文献。利用InCites平台和VOSviewer 1.6.8可视化分析工具总结文献发表情况、高被引论文、全球核心研究国家/地区,并进行主题聚类,结合相关文献的具体内容进行阐述,分析研究热点。结果截至2021年11月22日,共检索到12299篇文献,2016年至2021年全球乙型肝炎相关研究文献发表数量分别为2045篇、1996篇、2039篇、2118篇、2186篇和1915篇。中国内地(大陆)是发文量最多的国家/地区(4422篇,35.95%),篇均被引频次为7.46,美国发文量排在第2位(1949篇,15.85%),篇均被引频次为13.78。关键词主题聚类后得到的主要研究方向为:乙型肝炎病毒(hepatitis B virus,HBV)感染及HBV与丙型肝炎病毒、人类免疫缺陷病毒等的重叠感染、原发性肝细胞癌、抗病毒治疗与乙型肝炎治愈、HBV病毒学、HBV与宿主免疫、HBV再激活、HBV疫苗等。结论近6年全球乙型肝炎领域的研究集中于乙型肝炎流行病学及管理,乙型肝炎相关肝癌的预测与预防,乙型肝炎治愈与治疗优化,乙型肝炎发生、发展过程中HBV病毒学与宿主免疫机制等。全球乙型肝炎相关研究的文献发表数量相对平稳。中国内地(大陆)研究数量处于国际领先水平,但研究影响力尚需进一步扩大。Objective To analyze the hotspots and trends of global researches in the field of hepatitis B from 2016 to 2021.Methods Based on the Web of Science Core Collection Database,the indexed"article"and"review"related to hepatitis B from January 1,2016 to November 22,2021 were collected.Using InCites and VOSviewer 1.6.8 to cluster the published features,highly cited papers,key research directions and subject headings.And combined with the specific content of the literature,a summary of research hotspots was formed and analyzed.Results As of November 22,2021,a total of 12299 articles were retrieved.From 2016 to 2021,the numbers of global hepatitis B-related research publications were 2045,1996,2039,2118,2186 and 1915,respectively.China′s mainland published the most papers(4422 pieces,35.95%),with the average citation frequency of only 7.46,and the United States ranked second in terms of the number of papers published(1949 pieces,15.85%),with the average citation frequency of 13.78.The hotspots obtained after the clustering of keyword topics were hepatitis B virus(HBV)infection,coinfections of HBV and hepatitis C virus/human immunodeficiency virus,primary hepatocellular carcinoma,antiviral therapy and hepatitis B cure,HBV virology,HBV and immunology,HBV reactivation,HBV vaccine,etc.Conclusions In the past six years,global researches in the field of hepatitis B have focused on hepatitis B epidemiology and management,prediction and prevention of hepatitis B-related liver cancer,hepatitis B cure and treatment optimization,HBV virology and host immune mechanism in the development of hepatitis B,etc.The number of published papers in the field of hepatitis B keeps relatively stable.The number of researches in China′s mainland is at the international leading level,but the influence of researches needs to be further improved.

关 键 词：乙型肝炎 文献计量学 研究热点 

分 类 号：K512.62[历史地理—历史学]