Subcutaneous infection caused by Mycobacterium abscessus following cosmetic injections of botulinum toxin:A case report  

作　　者：Lin Deng Ying-Zhi Luo Fang Liu Xiao-Hong Yu 

机构地区：[1]Department of Dermatology,Affiliated Hangzhou First People’s Hospital,Zhejiang University School of Medicine,Hangzhou 310006,Zhejiang Province,China [2]Department of Dermatology,Jinling Hospital,Nanjing 210002,Jiangsu Province,China

出　　处：《World Journal of Clinical Cases》2022年第18期6141-6147,共7页世界临床病例杂志

摘　　要：BACKGROUND In recent years,the cosmetic intervention related infections caused by nontuberculous mycobacteria(NTM)are increasing as the informal cosmetic treatments are performed.However,many dermatologists are inexperienced in the diagnosis and management of similar cases.Here we report a case of subcutaneous infection caused by Mycobacterium abscessus(M.abscessus)following cosmetic injections of botulinum toxin.CASE SUMMARY A 53-year-old woman presented with multiple abscesses and nodules on her forehead and both temporal sites for half a month after cosmetic injections of botulinum toxin.Her lesions did not show any alleviation after 2-wk prescription of antibiotics.Laboratory examinations indicated that she had no sign of immunodeficiency and the whole body of computed tomography did not find any systemic infection or diseases.The pathology of skin tissue showed inflammatory cell infiltration with the negative results of Periodic acid Schiff(PAS)and Acidfast staining and the culture yielded no microbiome.Afterwards,the puncture on abscess was performed and M.abscessus was successfully isolated.The pathogen was identified by acid-fast staining and DNA sequencing.The patient was treated with the strategy of clarithromycin,ofloxacin,and amikacin according to the result of drug sensitivity test and got complete remission of the lesions.CONCLUSION The case presents the whole process of diagnosis and management of NTM infection after cosmetic intervention and highlights the diagnostic thoughts.In a word,the mycobacterium infection should be aware in patients after cosmetic performance.

关 键 词：Mycobacterium abscesses Skin infection Cosmetic injection Nontuberculous mycobacteria Case report 

分 类 号：R632[医药卫生—外科学]