Four-year experience with more than 1000 cases of total laparoscopic liver resection in a single center  

作　　者：Xiang Lan Hai-Li Zhang Hua Zhang Yu-Fu Peng Fei Liu Bo Li Yong-Gang Wei 

机构地区：[1]Department of Hepatobiliary Surgery,The First Affiliated Hospital,Chongqing Medical University,Chongqing 400016,China [2]Department of Liver Surgery&Liver Transplantation Center,Sichuan University West China Hospital,Chengdu 610041,Sichuan Province,China

出　　处：《World Journal of Gastroenterology》2022年第25期2968-2980,共13页世界胃肠病学杂志（英文版）

基　　金：Supported by Sichuan Provincial Key Project-Science and Technology Project Plan,No.2019yfs0372.

摘　　要：BACKGROUND Laparoscopic liver resection(LLR)has become a safe surgical procedure that needs additional summarization.AIM To review 4 years of total LLR surgeries,exceeding 1000 cases,which were performed at a single center.METHODS Patients who underwent LLR at West China Hospital of Sichuan University between January 2015 and December 2018 were identified.Surgical details,including the interventional year,category of liver disease,and malignant liver tumors prognosis,were evaluated.The learning curve for LLR was evaluated using the cumulative sum method.The Kaplan-Meier method was used to perform survival analysis.RESULTS Ultimately,1098 patients were identified.Hepatocellular carcinoma(HCC)was the most common disease that led to the need for LLR at the center(n=462,42.08%).The average operation time was 216.94±98.51 min.The conversion rate was 1.82%(20/1098).The complication rate was 9.20%(from grade II to V).The 1-year and 3-year overall survival rates of HCC patients were 89.7%and 81.9%,respectively.The learning curve was grouped into two phases for local resection(cases 1-106 and 107-373),three phases for anatomical segmentectomy(cases 1-44,45-74 and 75-120),and three phases for hemihepatectomy(cases 1-17,18-48 and CONCLUSION LLR may be considered a first-line surgical intervention for liver resection that can be performed safely for a variety of primary,secondary,and recurrent liver tumors and for benign diseases once technical competence is proficiently attained.

关 键 词：Laparoscopic liver resection Single-center experience Learning curve LIVER 

分 类 号：R657.3[医药卫生—外科学]